{"id":"W4315780670","doi":"10.1097/01.hjh.0000912940.32611.ca","title":"S-07-4: VASCULAR SMOOTH MUSCLE CELL PROTEOME AND PHENOTYPIC SWITCHING IN HUMAN HYPERTENSION ARE NOX5-DEPENDENT","year":2023,"lang":"en","type":"article","venue":"Journal of Hypertension","topic":"Atherosclerosis and Cardiovascular Diseases","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Proteome; Downregulation and upregulation; Vascular smooth muscle; Cell biology; Medicine; Extracellular matrix; Molecular biology; Biology; Endocrinology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002483878,0.0002048293,0.0002497259,0.0002612665,0.000312404,0.0002915571,0.0001325261,0.0003712281,0.00823819],"category_scores_gemma":[0.0002067522,0.0001098108,0.0003445504,0.000244282,0.0001663281,0.0001638317,0.0002287216,0.0003166774,0.001209291],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001549672,"about_ca_system_score_gemma":0.000232491,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005309524,"about_ca_topic_score_gemma":0.0004306888,"domain_scores_codex":[0.9999005,0.00001503968,0.0000115406,0.00002757759,0.00002440366,0.0000208847],"domain_scores_gemma":[0.9998543,0.0000184789,0.00003181925,0.00001286865,0.00003518961,0.00004733713],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002357814,0.000221803,0.02121544,0.0003417977,0.00006345412,0.001290578,0.0001646942,0.00007262878,0.9575177,0.000205722,0.001824304,0.01472409],"study_design_scores_gemma":[0.0002309829,0.002540154,0.6612238,0.0000845856,0.0002569236,0.008019275,0.0003160812,0.001456619,0.3125709,0.0004397852,0.0128364,0.00002443282],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921277,0.001380982,0.001455877,0.0004508754,0.0001163967,0.00005344251,0.002116641,0.00008002452,0.002218176],"genre_scores_gemma":[0.9867868,0.001045673,0.001343068,0.0003009993,0.00009354584,0.00007579756,0.004492065,0.00002569801,0.005836267],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00823819,"threshold_uncertainty_score":0.02755952,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02421487272262463,"score_gpt":0.2137253996651119,"score_spread":0.1895105269424872,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}