{"id":"W4315782895","doi":"10.1007/s00277-022-05071-8","title":"Improved benefit of continuing luspatercept therapy: sub-analysis of patients with lower-risk MDS in the MEDALIST study","year":2023,"lang":"en","type":"article","venue":"Annals of Hematology","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre","funders":"National Center for Advancing Translational Sciences; Acceleron; Bristol-Myers Squibb","keywords":"Medicine; Myelodysplastic syndromes; Blood transfusion; Internal medicine; Serum ferritin; Anemia; Placebo; Ferritin; Hemoglobin; Surgery; Bone marrow","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001049137,0.0001555452,0.001145319,0.000768627,0.00002302768,0.000003769469,0.0003159748,0.0001001591,0.00007000547],"category_scores_gemma":[0.0002717842,0.00009239856,0.0001880623,0.001922043,0.0002242194,0.00004141964,0.00008889241,0.0002320432,0.000002301106],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001097947,"about_ca_system_score_gemma":0.00005741396,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001136517,"about_ca_topic_score_gemma":0.0007901714,"domain_scores_codex":[0.9980201,0.0002547058,0.0006307224,0.0002705103,0.0004839449,0.0003400044],"domain_scores_gemma":[0.9979473,0.0004600033,0.0004301636,0.0006499182,0.0004641516,0.0000484408],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00153516,0.0009316935,0.9863797,0.00007334523,0.00207504,0.00004323196,0.005021035,0.00002749346,0.001416768,0.00005578668,0.000222798,0.002217951],"study_design_scores_gemma":[0.003690566,0.002686598,0.9746896,0.00005012322,0.0005515339,0.000002868821,0.003273864,0.0008712273,0.01401683,0.00004537258,0.00002512599,0.00009626563],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980774,0.0001547908,0.000008271291,0.000751494,0.00002190569,0.0008258382,0.00005731557,0.000013579,0.00008942139],"genre_scores_gemma":[0.9994954,0.0002209125,0.00001950004,0.0001019314,0.000006700277,0.00004196087,0.00006697106,0.00001905053,0.00002758097],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01260007,"threshold_uncertainty_score":0.3767904,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03680524295353615,"score_gpt":0.3407965031223594,"score_spread":0.3039912601688233,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}