{"id":"W4315795805","doi":"10.3390/biom13010152","title":"FK506-Binding Protein 2 Participates in Proinsulin Folding","year":2023,"lang":"en","type":"article","venue":"Biomolecules","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Punjab Educational Endowment Fund; Augustinus Fonden","keywords":"Proinsulin; Protein folding; Foldase; Chaperone (clinical); Chemistry; Biochemistry; Protein disulfide-isomerase; Cell biology; Insulin; Biology; Enzyme; Endocrinology; Gene; GroEL","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000769387,0.0004390033,0.0002189565,0.0001912786,0.0003205977,0.0003161745,0.000117627,0.0003968709,0.001188702],"category_scores_gemma":[0.00007313897,0.0001085903,0.0002396617,0.0001453245,0.0001364774,0.0002014251,0.0001576783,0.0002321993,0.0005994913],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003212022,"about_ca_system_score_gemma":0.0001731382,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008924527,"about_ca_topic_score_gemma":0.0006219284,"domain_scores_codex":[0.9999099,0.00001338871,0.000006975061,0.00003497086,0.00001291427,0.00002181359],"domain_scores_gemma":[0.9999501,0.000005392835,0.00001604794,0.00000466352,0.000007631811,0.00001620254],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003611536,0.00003381614,0.002371978,0.0001164539,0.00001671555,0.0005058491,0.00003302488,0.0001916334,0.988947,0.0005459116,0.0002417066,0.006634895],"study_design_scores_gemma":[0.00004197783,0.0003905329,0.07172764,0.00002796438,0.00005182597,0.003349506,0.0001084224,0.003095356,0.904601,0.0009600784,0.01561726,0.00002850965],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.965093,0.01730971,0.01185873,0.0004911697,0.000122059,0.00004084582,0.000604891,0.0002305592,0.004249116],"genre_scores_gemma":[0.9916991,0.002178488,0.002869161,0.00005795677,0.00002248056,0.00001153895,0.000355554,0.000009283949,0.002796462],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001188702,"threshold_uncertainty_score":0.003976583,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02821173877459252,"score_gpt":0.2932038944211096,"score_spread":0.2649921556465171,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}