{"id":"W4315796280","doi":"10.3389/fped.2022.1060843","title":"Protocol for a multicenter, double-blind, randomized, placebo-controlled phase III trial of the inhaled β2-adrenergic receptor agonist salbutamol for transient tachypnea of the newborn (the REFSAL trial)","year":2023,"lang":"en","type":"article","venue":"Frontiers in Pediatrics","topic":"Neonatal Respiratory Health Research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Agencja Badań Medycznych","keywords":"Medicine; Salbutamol; Anesthesia; Respiratory distress; Placebo; Neonatal intensive care unit; Intensive care; Tachypnea; Asthma; Internal medicine; Pediatrics; Intensive care medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02132813,0.006402789,0.008599317,0.001797856,0.003322303,0.002720045,0.003533876,0.007186143,0.1094684],"category_scores_gemma":[0.01758475,0.003134544,0.003670494,0.002172618,0.003645337,0.002576027,0.001937961,0.01090112,0.02159647],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002937499,"about_ca_system_score_gemma":0.01239118,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00127834,"about_ca_topic_score_gemma":0.002652386,"domain_scores_codex":[0.9861825,0.008035092,0.001081631,0.001788361,0.001512456,0.001399966],"domain_scores_gemma":[0.9922111,0.001442017,0.001479817,0.001374292,0.001618789,0.00187403],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8734864,0.01385015,0.0008885317,0.01299612,0.001396222,0.0004047826,0.0002982435,0.001705783,0.004313689,0.008743643,0.0435751,0.03834129],"study_design_scores_gemma":[0.8859975,0.02865414,0.001498466,0.002051319,0.0006139615,0.0001198994,0.00006528213,0.001687288,0.001089237,0.002470467,0.07564149,0.0001109392],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.001702336,0.0003541975,0.002099586,0.0002918349,0.001022777,0.9907863,0.002086184,0.0001400043,0.001516782],"genre_scores_gemma":[0.002049449,0.0001519684,0.002413652,0.00036828,0.0001283275,0.99362,0.0003506802,0.000009777884,0.000907829],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.1094684,"threshold_uncertainty_score":0.3662083,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06633378559283547,"score_gpt":0.4026862092643081,"score_spread":0.3363524236714727,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}