{"id":"W4315796280","doi":"10.3389/fped.2022.1060843","title":"Protocol for a multicenter, double-blind, randomized, placebo-controlled phase III trial of the inhaled β2-adrenergic receptor agonist salbutamol for transient tachypnea of the newborn (the REFSAL trial)","year":2023,"lang":"en","type":"article","venue":"Frontiers in Pediatrics","topic":"Neonatal Respiratory Health Research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Agencja Badań Medycznych","keywords":"Medicine; Salbutamol; Anesthesia; Respiratory distress; Placebo; Neonatal intensive care unit; Intensive care; Tachypnea; Asthma; Internal medicine; Pediatrics; Intensive care medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008053784,0.000378974,0.001968377,0.0004941763,0.0003226395,0.00003395005,0.0008798395,0.0003366822,0.00001748088],"category_scores_gemma":[0.007308229,0.0001918678,0.001412168,0.0017336,0.0005116927,0.00007923465,0.0001344589,0.0006596788,0.000001966951],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003066994,"about_ca_system_score_gemma":0.002203054,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008633924,"about_ca_topic_score_gemma":0.00004972356,"domain_scores_codex":[0.9938852,0.001116531,0.002313,0.0005330672,0.001342852,0.0008093037],"domain_scores_gemma":[0.9937293,0.003335874,0.001200016,0.0009895198,0.0005254102,0.0002198661],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9752283,0.001267859,0.000031899,0.001430469,0.0001776857,0.000003583965,0.0005181278,0.00006811894,0.0001308485,0.00005427353,0.01143015,0.00965867],"study_design_scores_gemma":[0.9360238,0.001997099,0.000002361026,0.00009261142,0.0005357026,0.000001206033,0.0002623289,0.005166816,0.001094519,0.00009253473,0.0545769,0.0001540949],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.114215,0.0003534862,0.00448091,0.002744038,0.0046688,0.8730577,0.0003214428,0.0000559721,0.0001026327],"genre_scores_gemma":[0.02335613,0.0001761974,0.002727421,0.0002749755,0.002258452,0.968917,0.0000704569,0.0001368463,0.002082554],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.09585925,"threshold_uncertainty_score":0.8749161,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06633378559283547,"score_gpt":0.4026862092643081,"score_spread":0.3363524236714727,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}