{"id":"W4315880768","doi":"10.1177/07067437221150508","title":"Feasibility, Acceptability, and Safety of Faecal Microbiota Transplantation in the Treatment of Major Depressive Disorder: A Pilot Randomized Controlled Trial","year":2023,"lang":"en","type":"article","venue":"The Canadian Journal of Psychiatry","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":71,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Wilson Foundation","keywords":"Major depressive disorder; Medicine; Adverse effect; Randomized controlled trial; Population; Placebo; Blinding; Transplantation; Quality of life (healthcare); Clinical trial; Internal medicine; Psychiatry; Mood; Alternative medicine; Nursing","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006695552,0.001531958,0.002839154,0.0005805652,0.000956694,0.001433221,0.001184926,0.003455897,0.01342918],"category_scores_gemma":[0.01126609,0.0008707113,0.003039703,0.0005361696,0.001949188,0.001682646,0.00096642,0.003514421,0.001597846],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009944532,"about_ca_system_score_gemma":0.002719027,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001011133,"about_ca_topic_score_gemma":0.001820246,"domain_scores_codex":[0.9952827,0.003262829,0.0003757794,0.0004294748,0.0002883636,0.000360912],"domain_scores_gemma":[0.993597,0.00265053,0.001519015,0.0005195476,0.0004979938,0.001215857],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9708781,0.01226596,0.0004768171,0.001148549,0.000720359,0.00004064763,0.0001062229,0.0001110336,0.0006882756,0.00009571466,0.0004611679,0.01300714],"study_design_scores_gemma":[0.8995302,0.09783886,0.001183893,0.0001170148,0.0003857047,0.0000150443,0.0000348255,0.0001644075,0.0001303176,0.0001216538,0.00046689,0.00001121898],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8716407,0.006349617,0.003082643,0.002323766,0.001643484,0.1081559,0.001909856,0.0003143729,0.004579579],"genre_scores_gemma":[0.9048554,0.002411231,0.006398228,0.001627228,0.0008977677,0.08098003,0.0004887442,0.00003014063,0.002311205],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01342918,"threshold_uncertainty_score":0.04492515,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.012865991582114,"score_gpt":0.2789407878417132,"score_spread":0.2660747962595992,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}