{"id":"W4316039532","doi":"10.3390/cancers15020492","title":"The Expanding Role of Cancer Stem Cell Marker ALDH1A3 in Cancer and Beyond","year":2023,"lang":"en","type":"review","venue":"Cancers","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"Nova Scotia Health Authority; Dalhousie University","funders":"Canadian Institutes of Health Research; Killam Trusts; Dalhousie University; Dalhousie Medical Research Foundation; Research Nova Scotia; Beatrice Hunter Cancer Research Institute; Cancer Research Institute","keywords":"Aldehyde dehydrogenase; Cancer stem cell; Cancer; Biology; Cancer research; Metastasis; Epigenetics; Stem cell; Cancer cell; Cell biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003399526,0.0003689663,0.001602775,0.0002040156,0.00007882543,0.00002416881,0.0001753101,0.0001937744,0.0001225689],"category_scores_gemma":[0.000009109285,0.0002446162,0.0003054139,0.0006578521,0.000195007,0.0000372444,0.0001001962,0.000426176,0.000006236873],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002228546,"about_ca_system_score_gemma":0.002784343,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00664685,"about_ca_topic_score_gemma":0.005166049,"domain_scores_codex":[0.9980709,0.00006400823,0.0006468743,0.0004696104,0.000295372,0.0004532213],"domain_scores_gemma":[0.998766,0.0002084175,0.000413674,0.0003941862,0.00005780027,0.0001598957],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004298406,0.00000569126,0.000163159,0.01534219,0.0002671666,0.00001253918,0.0002487554,0.00001019101,0.00001582474,0.0000200263,0.002390405,0.9814811],"study_design_scores_gemma":[0.0005374681,0.00003524802,0.00003762067,0.01359515,0.001242101,0.000003967478,0.0007410831,0.00001191639,0.00009047298,0.00001124267,0.9834619,0.0002318426],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005112633,0.9946874,3.768494e-7,0.00007514554,0.0008130441,0.0009964163,0.0002842789,0.00002230221,0.002609757],"genre_scores_gemma":[0.0001532573,0.9912277,0.00001203381,0.00007290311,0.0002904346,0.0009352408,0.0000148814,0.0001021932,0.007191365],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9812492,"threshold_uncertainty_score":0.999968,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0525514051508234,"score_gpt":0.3636391897432752,"score_spread":0.3110877845924518,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}