{"id":"W4316077727","doi":"10.14309/01.ajg.0000859576.23012.a3","title":"S734 Etrasimod 2mg Once Daily as Treatment for Patients With Moderately to Severely Active Ulcerative Colitis: Topline and Subgroup Analysis From ELEVATE UC 52 and ELEVATE UC 12","year":2022,"lang":"en","type":"article","venue":"The American Journal of Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Medicine; Ulcerative colitis; Clinical endpoint; Placebo; Internal medicine; Gastroenterology; Subgroup analysis; Clinical trial; Confidence interval; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001688041,0.00126711,0.00446753,0.0008717597,0.0002857494,0.001067939,0.0004865257,0.0009144538,0.003583362],"category_scores_gemma":[0.001600756,0.0003543691,0.00846402,0.0008668132,0.0003066278,0.0005895467,0.0005330825,0.001038125,0.0003353028],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005597443,"about_ca_system_score_gemma":0.0008537617,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001201816,"about_ca_topic_score_gemma":0.004767897,"domain_scores_codex":[0.9988363,0.0004825601,0.0002284767,0.0001617052,0.0001280711,0.0001628449],"domain_scores_gemma":[0.9993912,0.000208472,0.000165983,0.00007536148,0.00005405401,0.0001049541],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8689632,0.0008198427,0.02287583,0.005253232,0.04901065,0.0004666043,0.0001612372,0.001155727,0.006374137,0.0002011721,0.002841908,0.04187654],"study_design_scores_gemma":[0.6110944,0.08593377,0.1481139,0.001350241,0.129216,0.001114309,0.0006565924,0.004487801,0.00268162,0.0017774,0.01333832,0.0002357541],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9396228,0.04701013,0.001083668,0.0007546505,0.0005972445,0.002893914,0.004900268,0.00009907588,0.003038273],"genre_scores_gemma":[0.9883578,0.004963122,0.0005905968,0.0006294894,0.0003825888,0.001432592,0.002451658,0.00001579432,0.001176324],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00446753,"threshold_uncertainty_score":0.01198757,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005346714801996158,"score_gpt":0.2302140190801394,"score_spread":0.2248673042781433,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}