{"id":"W4316077799","doi":"10.14309/01.ajg.0000902184.86593.fc","title":"S749 Mirikizumab Improves Work Productivity and Activity Impairment Questionnaire Scores in Moderately-to-Severely Active UC: The LUCENT-1 and LUCENT-2 Randomized, Double-Blind, Placebo-Controlled Phase 3 Studies","year":2022,"lang":"en","type":"article","venue":"The American Journal of Gastroenterology","topic":"Microscopic Colitis","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Medicine; Absenteeism; Placebo; Randomization; Work productivity; Clinical trial; Presenteeism; Internal medicine; Physical therapy; Surgery; Productivity; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002421864,0.0002973209,0.001895483,0.0002693239,0.0003192246,0.00003492086,0.0002261712,0.00002200275,0.00001295564],"category_scores_gemma":[0.000328913,0.0001703355,0.0001875311,0.00026319,0.001210472,0.0001215249,0.0003862059,0.0008523752,4.563252e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003638726,"about_ca_system_score_gemma":0.0001612091,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002471018,"about_ca_topic_score_gemma":0.0002310426,"domain_scores_codex":[0.9960548,0.002103645,0.0006345951,0.0003576587,0.0003565086,0.0004928177],"domain_scores_gemma":[0.9978344,0.0005253,0.0009750404,0.000315362,0.0001780221,0.0001718292],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.979921,0.0006662575,0.003695396,0.00002481823,0.001107035,0.00007276081,0.004960249,0.0001161526,0.0007144415,0.000006751713,0.0001243797,0.00859069],"study_design_scores_gemma":[0.8182694,0.02023369,0.1521546,0.0002066507,0.000832125,0.002963151,0.004152325,0.000276821,0.0005073366,0.0001986483,0.00003835645,0.0001669611],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9684165,0.00117654,0.000215708,0.02708938,0.0002740315,0.0028035,0.000008829112,0.00001152928,0.000003955731],"genre_scores_gemma":[0.9979311,0.00036802,0.000128976,0.0009530804,0.0001586771,0.0003933706,8.655137e-7,0.00002219911,0.00004372862],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1616517,"threshold_uncertainty_score":0.6946081,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01982123441935932,"score_gpt":0.3212012865004992,"score_spread":0.3013800520811399,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}