{"id":"W4316077799","doi":"10.14309/01.ajg.0000902184.86593.fc","title":"S749 Mirikizumab Improves Work Productivity and Activity Impairment Questionnaire Scores in Moderately-to-Severely Active UC: The LUCENT-1 and LUCENT-2 Randomized, Double-Blind, Placebo-Controlled Phase 3 Studies","year":2022,"lang":"en","type":"article","venue":"The American Journal of Gastroenterology","topic":"Microscopic Colitis","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Medicine; Absenteeism; Placebo; Randomization; Work productivity; Clinical trial; Presenteeism; Internal medicine; Physical therapy; Surgery; Productivity; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00227985,0.0009185129,0.002371822,0.0005344692,0.0003914575,0.0008027044,0.0007008875,0.001095847,0.007124413],"category_scores_gemma":[0.001285727,0.0004473265,0.002125567,0.0004537057,0.0007136838,0.0005739874,0.0002429777,0.00114137,0.000813567],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005246354,"about_ca_system_score_gemma":0.0009677094,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004395051,"about_ca_topic_score_gemma":0.001408822,"domain_scores_codex":[0.9990643,0.0005626302,0.00008873445,0.00009310721,0.000105195,0.0000860779],"domain_scores_gemma":[0.9991819,0.0002363526,0.0002754715,0.00005632594,0.00005987431,0.0001900147],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9209266,0.007423283,0.002182189,0.001551166,0.002620238,0.0000644762,0.00005812188,0.0002454146,0.01089502,0.00008150697,0.001226706,0.05272531],"study_design_scores_gemma":[0.8045968,0.1788987,0.01128735,0.0001116583,0.00152548,0.0001115863,0.00002168386,0.0002719735,0.001497203,0.00008164243,0.001571536,0.00002441335],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9806615,0.0124746,0.0005605897,0.0005044467,0.0001994533,0.002575068,0.0009349922,0.0001351557,0.001954303],"genre_scores_gemma":[0.9896003,0.00377525,0.001316578,0.0007234282,0.0003103143,0.001724774,0.0009782104,0.00001842521,0.001552854],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007124413,"threshold_uncertainty_score":0.02383357,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01982123441935932,"score_gpt":0.3212012865004992,"score_spread":0.3013800520811399,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}