{"id":"W4317035829","doi":"10.1186/s12934-022-02004-y","title":"Novel context-specific genome-scale modelling explores the potential of triacylglycerol production by Chlamydomonas reinhardtii","year":2023,"lang":"en","type":"article","venue":"Microbial Cell Factories","topic":"Microbial Metabolic Engineering and Bioproduction","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Queen's University; Government of Canada; Government of Ontario; Ontario Genomics; Genome Canada","keywords":"Chlamydomonas reinhardtii; Context (archaeology); Computational biology; Computer science; Overproduction; Overlay; Biology; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002061104,0.0002142147,0.0002148021,0.0000589418,0.0001760422,0.00003813232,0.0002222757,0.0001446652,0.00001329324],"category_scores_gemma":[0.0000228689,0.0001713332,0.0001379799,0.0002407543,0.0001449575,0.00001123881,0.0000884346,0.0001358824,0.00001574871],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001349873,"about_ca_system_score_gemma":0.00003520655,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007484719,"about_ca_topic_score_gemma":0.000009564909,"domain_scores_codex":[0.9987825,0.00003812847,0.0003212809,0.000441891,0.0001322118,0.0002840405],"domain_scores_gemma":[0.9992946,0.000004228062,0.0001234411,0.0003918063,0.0001448572,0.0000410849],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000174987,0.00005475147,0.000008341915,0.00003586811,0.00003076137,2.425243e-7,0.0002985218,0.008480469,0.9813383,0.000005897354,0.009161492,0.0004104001],"study_design_scores_gemma":[0.0003470426,0.00005216197,0.00005748292,0.000006820834,0.00001901001,0.000006950997,0.0002561279,0.00004019694,0.8309318,0.000004894348,0.1681114,0.0001661279],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9799274,0.002076148,0.0155322,0.0002428775,0.001664752,0.00032372,0.0001538831,0.00005797767,0.00002103004],"genre_scores_gemma":[0.9939476,0.001662743,0.0002822733,0.00001612737,0.001282702,0.00001722643,0.0005062697,0.00004010669,0.002244911],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1589499,"threshold_uncertainty_score":0.6986765,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01350484682525954,"score_gpt":0.1952744615598387,"score_spread":0.1817696147345791,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}