{"id":"W4317039843","doi":"10.1021/acsptsci.2c00232","title":"Development of Brain-Derived Bioscaffolds for Neural Progenitor Cell Culture","year":2023,"lang":"en","type":"article","venue":"ACS Pharmacology & Translational Science","topic":"Tissue Engineering and Regenerative Medicine","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Schulich School of Medicine and Dentistry, Western University","keywords":"Microcarrier; Decellularization; Progenitor cell; Cell biology; Regenerative medicine; Tissue engineering; Extracellular matrix; Neural stem cell; Regeneration (biology); Neurosphere; Cell culture; Chemistry; Stem cell; Biology; Cellular differentiation; Cell; Biomedical engineering; Adult stem cell; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002271393,0.0004016694,0.0001752299,0.0003700294,0.0001578001,0.0002761389,0.0002348656,0.0003132812,0.0005403416],"category_scores_gemma":[0.0002770664,0.0001280376,0.0002217995,0.0001429242,0.0001379632,0.0002407904,0.0002493723,0.0003342528,0.0003372565],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002377889,"about_ca_system_score_gemma":0.0004069192,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007843879,"about_ca_topic_score_gemma":0.001968906,"domain_scores_codex":[0.9998924,0.000007638207,0.00001483542,0.00001966649,0.00004879493,0.00001684025],"domain_scores_gemma":[0.9998693,0.00002457132,0.0000244355,0.000009642246,0.00005077161,0.00002126219],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000008979277,0.000005832355,0.00007104714,0.00002778648,0.00000185365,0.00003794532,0.00001142581,0.00006585723,0.9977633,0.00006315316,0.00002069491,0.001922221],"study_design_scores_gemma":[0.000002320658,0.00005255692,0.0005815019,0.000009307571,0.000008393099,0.0001405227,0.00001184142,0.0005266799,0.9964815,0.00003288407,0.002148286,0.000004002433],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8789316,0.00739932,0.1071458,0.0001828541,0.0001558029,0.0005346775,0.001277945,0.0004862638,0.003885689],"genre_scores_gemma":[0.8207982,0.007628877,0.1651696,0.0001554606,0.00005294222,0.0006362455,0.001947352,0.0000922519,0.003518994],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007843879,"threshold_uncertainty_score":0.00180763,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03288663223776335,"score_gpt":0.349117025868888,"score_spread":0.3162303936311247,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}