{"id":"W4317378094","doi":"10.1016/j.biopsych.2022.12.023","title":"Increase in Serotonin Transporter Binding in Patients With Premenstrual Dysphoric Disorder Across the Menstrual Cycle: A Case-Control Longitudinal Neuroreceptor Ligand Positron Emission Tomography Imaging Study","year":2023,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Menstrual Health and Disorders","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"Universität Leipzig; Max-Planck-Gesellschaft","keywords":"Premenstrual dysphoric disorder; Serotonin transporter; Internal medicine; Menstrual cycle; Binding potential; Endocrinology; Serotonin; Psychology; Major depressive disorder; Serotonergic; Neurochemical; Positron emission tomography; Mood; Medicine; Psychiatry; Neuroscience; Hormone; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006568065,0.0003673093,0.0004959504,0.0002488046,0.0002701556,0.00003047457,0.0001541028,0.0001495692,0.00004036834],"category_scores_gemma":[0.00005197518,0.0002070367,0.0001000423,0.001308441,0.0001555363,0.00009487751,0.00004589725,0.0006013754,0.00001005861],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005545683,"about_ca_system_score_gemma":0.00009488453,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005911041,"about_ca_topic_score_gemma":0.0007913813,"domain_scores_codex":[0.9971277,0.0002548191,0.0006412959,0.0007156073,0.0003694581,0.0008911805],"domain_scores_gemma":[0.9991035,0.000104081,0.0001380413,0.0003120118,0.00004765109,0.0002946561],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.004380396,0.001441385,0.9890684,0.00006157576,0.00003576383,0.0003148977,0.0006711279,0.00001452485,0.00003162759,0.000003024687,0.00007203292,0.003905196],"study_design_scores_gemma":[0.01421542,0.002356596,0.9782364,0.0001181168,0.00004764758,0.00006892846,0.004490608,0.0001737434,0.000003006607,0.00002571133,0.00001751975,0.0002463144],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957345,0.0001585289,0.000006334863,0.0006883703,0.0003754447,0.002798726,0.00008643955,0.0001076188,0.00004402685],"genre_scores_gemma":[0.9991608,0.00001192378,0.00007121202,0.0003658556,0.00007934946,0.0001872308,0.00008616241,0.00002880453,0.000008714211],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01083206,"threshold_uncertainty_score":0.8442712,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01144246830722689,"score_gpt":0.2857739298163591,"score_spread":0.2743314615091322,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}