{"id":"W4317388020","doi":"10.1038/s12276-023-00926-0","title":"Chromatin and noncoding RNA-mediated mechanisms of gastric tumorigenesis","year":2023,"lang":"en","type":"review","venue":"Experimental & Molecular Medicine","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research; Hospital for Sick Children","keywords":"Epigenetics; Carcinogenesis; Biology; Histone; DNA methylation; Chromatin; Long non-coding RNA; Non-coding RNA; Cancer epigenetics; Genetics; Chromatin remodeling; RNA; Cancer; DNA; Gene; Gene expression; Histone methyltransferase","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003326625,0.0004408064,0.00108487,0.0002341876,0.00005582173,0.000009680348,0.0002261981,0.0003076504,0.00003731535],"category_scores_gemma":[0.0001529307,0.0003722225,0.000210632,0.0003507741,0.0001481927,0.000002377752,0.0002260053,0.0001275778,0.00001275851],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003808811,"about_ca_system_score_gemma":0.0001003187,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000322495,"about_ca_topic_score_gemma":0.000001127186,"domain_scores_codex":[0.9979166,0.0001646948,0.0007251039,0.0005667031,0.0003446817,0.0002822035],"domain_scores_gemma":[0.99888,0.00004546159,0.0004392367,0.0004200989,0.00005252736,0.0001626192],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000006444044,0.00003939385,8.83962e-7,0.001528544,0.0001703109,0.00003173967,0.00004677796,8.314426e-7,0.9645259,0.000100464,0.00005840273,0.03349026],"study_design_scores_gemma":[0.0009617122,0.00153747,0.000008331062,0.005155973,0.0005230731,0.00004011331,0.0002409355,0.00001585345,0.8676183,0.0001151023,0.1231371,0.000646056],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003130049,0.9929322,0.002692136,0.00001273984,0.0002743476,0.0005710757,0.00003351044,0.00002354274,0.0003304022],"genre_scores_gemma":[0.00700984,0.9903689,0.001146626,0.00003300554,0.0002162481,0.0001019251,0.0008811911,0.0001207978,0.0001214549],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.1230787,"threshold_uncertainty_score":0.999873,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03486691753623231,"score_gpt":0.3511441497112882,"score_spread":0.3162772321750559,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}