{"id":"W4317390088","doi":"10.1099/mic.0.001272","title":"Do mitochondria use efflux pumps to protect their ribosomes from antibiotics?","year":2023,"lang":"en","type":"article","venue":"Microbiology","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Efflux; Ethidium bromide; Mitochondrion; Biology; Organelle; Antibiotics; Ribosome; Microbiology; Antimicrobial; Proteome; Biochemistry; Gene; RNA; DNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000950874,0.0004155082,0.0006690367,0.0003524868,0.0003640073,0.001441434,0.0004544181,0.001820021,0.001120576],"category_scores_gemma":[0.0008257941,0.0002849249,0.0004122843,0.0002357783,0.0008914474,0.002993007,0.0004182965,0.000565537,0.001549663],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003433481,"about_ca_system_score_gemma":0.0002542371,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001905069,"about_ca_topic_score_gemma":0.000385838,"domain_scores_codex":[0.9996856,0.00007889541,0.00002533803,0.00005705289,0.00005475829,0.00009834765],"domain_scores_gemma":[0.9994316,0.0001398404,0.0001790646,0.00008919739,0.00007821633,0.00008214123],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005746467,0.0001256167,0.01330172,0.0006794985,0.00008328244,0.001268707,0.0004491618,0.0003803585,0.9315015,0.009409786,0.001146314,0.04107939],"study_design_scores_gemma":[0.000140473,0.001866364,0.076857,0.0003987405,0.0002064356,0.008933209,0.003038419,0.006097869,0.796775,0.01846889,0.0870415,0.0001760997],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8602105,0.08036275,0.0331234,0.01508853,0.0005329777,0.00006445579,0.0002918273,0.0005450358,0.009780643],"genre_scores_gemma":[0.9670134,0.02376511,0.004797892,0.001259397,0.0002197375,0.00001839295,0.0001760987,0.00004295267,0.002707054],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001820021,"threshold_uncertainty_score":0.005028784,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0191262268129316,"score_gpt":0.2403690117641404,"score_spread":0.2212427849512088,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}