{"id":"W4317567968","doi":"10.1007/s40744-022-00529-7","title":"Patient Disease Trajectories in Rheumatoid Arthritis Patients Treated with Baricitinib 4-mg in Four Phase 3 Clinical Studies","year":2023,"lang":"en","type":"article","venue":"Rheumatology and Therapy","topic":"Rheumatoid Arthritis Research and Therapies","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Chugai Pharmaceutical; Genentech; Astellas Pharma; National Institute for Health and Care Research; Biogen; Celgene; Gilead Sciences; Nordic Pharma Group; Eisai; Daiichi Sankyo Europe; Sanofi; Amgen; Pfizer; Eli Lilly and Company; Bristol-Myers Squibb; GlaxoSmithKline","keywords":"Rheumatoid arthritis; Medicine; Disease; Dermatology; Arthritis; Internal medicine; Physical therapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01279697,0.0006696433,0.002065365,0.0008201672,0.0006659495,0.001332327,0.0005405546,0.0007567555,0.0008065846],"category_scores_gemma":[0.009853349,0.0004782218,0.0022425,0.001172303,0.000380814,0.0007107587,0.0008578562,0.001089367,0.0001525826],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001097815,"about_ca_system_score_gemma":0.001908576,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001065637,"about_ca_topic_score_gemma":0.002555647,"domain_scores_codex":[0.9954306,0.00304614,0.000431394,0.0004036514,0.0004351453,0.0002531402],"domain_scores_gemma":[0.9931202,0.002824434,0.002437292,0.0004399792,0.0007574178,0.000420717],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.1596509,0.004055239,0.6354467,0.002583701,0.01422619,0.0004914419,0.001853818,0.009496743,0.0172946,0.0005207174,0.002190412,0.1521897],"study_design_scores_gemma":[0.03544969,0.1012721,0.8080519,0.0007647836,0.01514272,0.001184741,0.001286126,0.0130033,0.008402209,0.001571318,0.01358614,0.000285],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910576,0.005215978,0.001243238,0.0001949013,0.00001843347,0.0008769183,0.0008425305,0.00003215615,0.0005181832],"genre_scores_gemma":[0.9931537,0.001032325,0.002098312,0.0002980954,0.00001373751,0.00102217,0.002155104,0.000009496337,0.0002171289],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01279697,"threshold_uncertainty_score":0.06767762,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03791251253965131,"score_gpt":0.3451770614039854,"score_spread":0.3072645488643341,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}