{"id":"W4317568027","doi":"10.1093/cid/ciad020","title":"Long-Acting Cabotegravir and Rilpivirine Dosed Every 2 Months in Adults With Human Immunodeficiency Virus 1 Type 1 Infection: 152-Week Results From ATLAS-2M, a Randomized, Open-Label, Phase 3b, Noninferiority Study","year":2023,"lang":"en","type":"article","venue":"Clinical Infectious Diseases","topic":"HIV/AIDS drug development and treatment","field":"Medicine","cited_by":124,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Regina","funders":"Janssen Research and Development; Gilead Sciences; Insmed; ViiV Healthcare; National Institutes of Health; Pfizer","keywords":"Rilpivirine; Medicine; Tolerability; Human immunodeficiency virus (HIV); Dosing; Regimen; Internal medicine; Viral load; Adverse effect; Virology; Antiretroviral therapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003365435,0.001137206,0.001756705,0.0003471263,0.0003609426,0.0008053124,0.0009650086,0.001264089,0.003952851],"category_scores_gemma":[0.001620756,0.0006377146,0.001409966,0.0003248611,0.000683262,0.0008604283,0.000391072,0.001819533,0.0007357271],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006828558,"about_ca_system_score_gemma":0.001206025,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008762518,"about_ca_topic_score_gemma":0.002565196,"domain_scores_codex":[0.9987695,0.0007951724,0.00007079498,0.0001359251,0.0001319027,0.00009659341],"domain_scores_gemma":[0.9987935,0.0002526396,0.0003182391,0.00009561414,0.0001006698,0.000439411],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9534002,0.01582481,0.005643723,0.0002925126,0.001103085,0.00004299085,0.00008322891,0.0003855048,0.004957574,0.0000738011,0.001387487,0.0168051],"study_design_scores_gemma":[0.8554331,0.1270405,0.0147616,0.00002201955,0.0006337042,0.00005828391,0.00002566154,0.0005176732,0.000629123,0.0000716471,0.0007863234,0.00002040079],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936314,0.001852331,0.0003116875,0.0002914524,0.00009201679,0.001438754,0.001271136,0.00005403485,0.001057144],"genre_scores_gemma":[0.9922109,0.0007698081,0.001178216,0.0006734849,0.0002002087,0.001981333,0.001708304,0.00001716892,0.001260474],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003952851,"threshold_uncertainty_score":0.01779836,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06474784941476527,"score_gpt":0.4037233714721519,"score_spread":0.3389755220573867,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}