{"id":"W4317663908","doi":"10.1016/j.bbrc.2023.01.068","title":"Apelin expression is downregulated in T cells in a murine model of chronic colitis","year":2023,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Apelin-related biomedical research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Japan Science and Technology Agency; T. Von Zastrow Foundation; Tokyo Medical and Dental University; Ministry of Education, Culture, Sports, Science and Technology; Canada Research Chairs; Japan Agency for Medical Research and Development; Japan Foundation for Applied Enzymology; Takeda Science Foundation","keywords":"Colitis; Lamina propria; Apelin; Pathogenesis; Immunology; Downregulation and upregulation; Ulcerative colitis; Cytokine; Medicine; Biology; Chemistry; Cancer research; Internal medicine; Receptor; Pathology; Biochemistry; Epithelium","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001016236,0.0001361414,0.0003606701,0.0005948375,0.00008218984,0.00001410765,0.000605264,0.0002854908,0.00006308317],"category_scores_gemma":[0.000775428,0.0001098405,0.00007730271,0.00284299,0.001462601,0.00004971429,0.001181589,0.001284136,0.0001038256],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002093063,"about_ca_system_score_gemma":0.0004016244,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000292564,"about_ca_topic_score_gemma":0.00002315297,"domain_scores_codex":[0.9973252,0.0002338593,0.0004912707,0.0003848149,0.0009289314,0.0006359059],"domain_scores_gemma":[0.997289,0.0009588146,0.00003897319,0.001063952,0.0002777084,0.0003715468],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002325455,0.0009209031,0.00009639516,0.0001887761,0.00001013214,0.00001249384,0.0001585551,0.000004453413,0.9917755,0.0003422237,0.002548487,0.003709548],"study_design_scores_gemma":[0.00217746,0.0003448993,0.01254478,0.001042508,0.00000903651,0.000002562257,0.0001393377,0.3406354,0.6396298,0.002568884,0.0007430397,0.0001622666],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9887086,0.0005460717,0.00001015759,0.009525229,0.000006217951,0.0005979195,0.00006467595,0.00003948183,0.0005016691],"genre_scores_gemma":[0.9940923,0.004380188,0.0005685826,0.00004744986,0.00003481338,0.0001129236,0.000137545,0.0000184521,0.0006077745],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3521456,"threshold_uncertainty_score":0.5579002,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1127758075646545,"score_gpt":0.4166059173082337,"score_spread":0.3038301097435792,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}