{"id":"W4317906507","doi":"10.1016/j.nicl.2023.103337","title":"Aerobic exercise increases brain vessel lumen size and blood flow in young adults with elevated blood pressure. Secondary analysis of the TEPHRA randomized clinical trial","year":2023,"lang":"en","type":"article","venue":"NeuroImage Clinical","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hotchkiss Brain Institute; University of Calgary","funders":"Royal Society; National Institute for Health and Care Research; Department of Health and Social Care; British Heart Foundation; Wellcome Trust","keywords":"Medicine; Randomized controlled trial; Blood pressure; Cerebral blood flow; Aerobic exercise; Body mass index; Transcranial Doppler; Anterior cerebral artery; Middle cerebral artery; Heart rate; Cardiology; Internal medicine; Ischemia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002869923,0.001858132,0.004002517,0.0005237537,0.0004181825,0.001302027,0.0006291575,0.00192228,0.01045207],"category_scores_gemma":[0.005811159,0.000601829,0.003714532,0.0005300491,0.0007221847,0.0009122099,0.0006309069,0.002328345,0.0008261856],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004379115,"about_ca_system_score_gemma":0.0008962383,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001303247,"about_ca_topic_score_gemma":0.001652817,"domain_scores_codex":[0.9983124,0.001000137,0.0001620603,0.000256101,0.00009451163,0.0001748003],"domain_scores_gemma":[0.9968094,0.001226487,0.0009464062,0.0002660093,0.0002211379,0.0005305386],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.9893266,0.001116949,0.0007066224,0.001231347,0.002273592,0.00002345913,0.00002050042,0.0001234599,0.0004865736,0.00004638153,0.0004406289,0.004203887],"study_design_scores_gemma":[0.963348,0.02733906,0.005121039,0.000108652,0.003029512,0.00002620753,0.00001412145,0.0003017736,0.0001906796,0.0001857185,0.0003206581,0.00001465241],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.961658,0.01065653,0.001546434,0.001103148,0.001211239,0.01352854,0.005300942,0.0002481025,0.004747112],"genre_scores_gemma":[0.9727134,0.003424105,0.002212534,0.001046491,0.0009442954,0.01349424,0.002434679,0.00003876872,0.003691501],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01045207,"threshold_uncertainty_score":0.03496563,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02391364188525166,"score_gpt":0.3512266330091204,"score_spread":0.3273129911238687,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}