{"id":"W4317939386","doi":"10.1097/pai.0000000000001102","title":"Estrogen/Progesterone Receptor Loss, CTNNB1 and KRAS Mutations Are Associated With Local Recurrence or Distant Metastasis in Low-Grade Endometrial Endometrioid Carcinoma","year":2023,"lang":"en","type":"article","venue":"Applied immunohistochemistry & molecular morphology","topic":"Endometrial and Cervical Cancer Treatments","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University; Saskatchewan Cancer Agency; University of Alberta; University of Saskatchewan; Lakeridge Health","funders":"","keywords":"KRAS; Medicine; Progesterone receptor; Metastasis; Internal medicine; Oncology; Immunohistochemistry; Cancer research; Exon; Estrogen receptor; Mutation; Cancer; Biology; Gene; Breast cancer; Colorectal cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003297437,0.0005155479,0.001087259,0.0005764003,0.0001379648,0.00003281968,0.0002425469,0.0003179471,0.0002269625],"category_scores_gemma":[0.0006936278,0.0004317816,0.0001564642,0.003901461,0.0006418054,0.00005063699,0.0001580912,0.0005760685,0.00004713554],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007580824,"about_ca_system_score_gemma":0.0002909698,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001607652,"about_ca_topic_score_gemma":0.000004064019,"domain_scores_codex":[0.9968877,0.0001068946,0.0007025662,0.0009646225,0.0005477642,0.0007904412],"domain_scores_gemma":[0.998063,0.0005513842,0.0003556252,0.0005966458,0.0001292579,0.0003040829],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005837739,0.0009188589,0.008101343,0.0002270797,0.0007661586,0.004087159,0.0001472777,0.00003029041,0.9746139,0.000146859,0.0001094897,0.005013846],"study_design_scores_gemma":[0.05085764,0.002180134,0.02479428,0.0004597582,0.001277918,0.0009813143,0.001113241,0.00003378628,0.9165322,0.0002029446,0.000390918,0.001175883],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945083,0.002899087,0.0003826389,0.0003456841,0.0001649489,0.00106504,0.0002663405,0.0001410195,0.0002269841],"genre_scores_gemma":[0.996555,0.0001938148,0.0005010545,0.0001664753,0.00004978924,0.0007773216,0.001528297,0.00007767346,0.0001505573],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05808172,"threshold_uncertainty_score":0.9998134,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01722658757633797,"score_gpt":0.2748814464179054,"score_spread":0.2576548588415674,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}