{"id":"W4317989676","doi":"10.1021/acs.chemrev.2c00350","title":"Reagents for Mass Cytometry","year":2023,"lang":"en","type":"review","venue":"Chemical Reviews","topic":"Cell Image Analysis Techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"Fluidigm (Canada); University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Fluidigm","keywords":"Mass cytometry; Chemistry; Reagent; Cytometry; Flow cytometry; Bioanalysis; Mass spectrometry; Inductively coupled plasma mass spectrometry; Resolution (logic); Chromatography; Nanotechnology; Molecular biology; Cell; Biochemistry; Computer science; Materials science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006723035,0.0004756658,0.002019755,0.0001121912,0.0000301591,0.00003253883,0.0006862302,0.000609343,0.00002792098],"category_scores_gemma":[0.001584027,0.0003720639,0.002019762,0.0004276042,0.00005629398,0.000001786352,0.0002345536,0.0002150677,0.0003636903],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005070519,"about_ca_system_score_gemma":0.00007680512,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":8.191537e-7,"about_ca_topic_score_gemma":4.05379e-7,"domain_scores_codex":[0.9976581,0.00008017296,0.0009685978,0.0008151053,0.0001285277,0.0003494959],"domain_scores_gemma":[0.9981763,0.00006567499,0.0004640582,0.001099337,0.00006515897,0.0001295161],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000001941592,0.00001801482,1.457906e-7,0.01667519,0.0001494949,0.000001878692,4.263713e-7,1.282732e-9,0.02345267,0.000002477036,0.2027143,0.7569835],"study_design_scores_gemma":[0.00005556446,0.00002396164,7.489917e-9,0.003820272,0.0008653144,0.000005548052,3.532313e-7,3.93485e-7,0.01590892,0.00003822292,0.9789122,0.0003692607],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[5.132839e-7,0.9935168,0.003962203,0.000004368092,0.00003886017,0.001556134,0.00003333143,0.00005632028,0.0008314694],"genre_scores_gemma":[1.192402e-7,0.9851472,0.004369368,0.0001018005,0.0005965837,0.001364322,0.00275016,0.0001328421,0.005537547],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.7761979,"threshold_uncertainty_score":0.9998731,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1022771006266547,"score_gpt":0.4297405171379918,"score_spread":0.3274634165113371,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}