{"id":"W4318022906","doi":"10.1016/j.modpat.2022.100085","title":"Grade and Estrogen Receptor Expression Identify a Subset of No Specific Molecular Profile Endometrial Carcinomas at a Very Low Risk of Disease-Specific Death","year":2023,"lang":"en","type":"article","venue":"Modern Pathology","topic":"Endometrial and Cervical Cancer Treatments","field":"Medicine","cited_by":104,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval; University of Saskatchewan; Université de Montréal; University of Manitoba; McMaster University; University of Toronto; Dalhousie University; University of Calgary; McGill University; University of British Columbia","funders":"Canadian Institutes of Health Research; BC Cancer Foundation; Vancouver Coastal Health Research Institute; Michael Smith Health Research BC","keywords":"Lymphovascular invasion; Oncology; Internal medicine; Estrogen receptor; Hazard ratio; Disease; Univariate analysis; Stage (stratigraphy); Medicine; Progesterone receptor; Immunohistochemistry; Pathology; Multivariate analysis; Biology; Cancer; Breast cancer; Metastasis; Confidence interval","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002533392,0.0002245852,0.0006744434,0.0004218523,0.00006055816,0.000006555274,0.0001170094,0.0001498512,0.0002673386],"category_scores_gemma":[0.0002547742,0.0001831506,0.0002353932,0.0005655534,0.0001606115,0.00004516224,0.0001927613,0.0001556345,0.00009144298],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009407097,"about_ca_system_score_gemma":0.00004859627,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002505165,"about_ca_topic_score_gemma":0.000001003966,"domain_scores_codex":[0.9980037,0.0002297248,0.0004611791,0.0005461874,0.000412431,0.0003467653],"domain_scores_gemma":[0.9986765,0.0002438884,0.0002362218,0.0004883582,0.0001087101,0.00024633],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.007531451,0.0004429329,0.2515939,0.0003119239,0.000120044,0.0007602839,0.0003152547,0.00001571888,0.7351567,0.00006280612,0.0005345849,0.00315438],"study_design_scores_gemma":[0.02245055,0.002201752,0.4102783,0.0002513205,0.0005270926,0.00006559141,0.00006747501,0.0002481299,0.5604538,0.001777706,0.001276019,0.0004022704],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914472,0.006302838,0.000210779,0.00005271932,0.0003837506,0.000706142,0.0007262783,0.00005364711,0.0001166605],"genre_scores_gemma":[0.9964508,0.001857753,0.0007363514,0.00001562022,0.0001709472,0.0001041512,0.0003937517,0.00004010336,0.0002305282],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1747029,"threshold_uncertainty_score":0.7468665,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0387300434373826,"score_gpt":0.2835103925904303,"score_spread":0.2447803491530477,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}