{"id":"W4318067840","doi":"10.1038/s41598-023-28369-7","title":"Neuronal chemokine concentration gradients mediate effects of embryonic ethanol exposure on ectopic hypocretin/orexin neurons and behavior in zebrafish","year":2023,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Zebrafish Biomedical Research Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institutes of Health; Bar-Ilan University; National Institute for Basic Biology; National Institute on Alcohol Abuse and Alcoholism; York University","keywords":"Lateral hypothalamus; Internal medicine; Biology; Endocrinology; Zebrafish; Orexin; Neuropeptide; Orexin-A; Neuroscience; Cell biology; Receptor; Hypothalamus; Chemistry; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007394772,0.0002595232,0.0001704453,0.0002044486,0.0001389471,0.0001912627,0.0001597781,0.0002261985,0.001463145],"category_scores_gemma":[0.00008404596,0.0002064591,0.0002231177,0.00006274351,0.0002762098,0.0002319397,0.0002481321,0.0006083786,0.0002381495],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006991646,"about_ca_system_score_gemma":0.0003218437,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005232239,"about_ca_topic_score_gemma":0.0104867,"domain_scores_codex":[0.9999088,0.00000766621,0.00000747183,0.00001978691,0.00002970758,0.00002651476],"domain_scores_gemma":[0.999936,0.000007354801,0.00002412506,0.000004886838,0.00001066578,0.00001707134],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002046354,0.000002993004,0.00007014122,0.000008729328,8.197563e-7,0.00001608831,0.000008939756,0.00002257693,0.9995916,0.00004168722,0.00001074942,0.0002050588],"study_design_scores_gemma":[0.00001108047,0.0001174605,0.01083216,0.000007749693,0.000008153987,0.00007104384,0.00005152093,0.0005948187,0.9873487,0.0000344003,0.0009153658,0.000007570679],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995066,0.0004700567,0.002243615,0.000104243,0.00001555604,0.000020244,0.0004098472,0.00006740289,0.001602987],"genre_scores_gemma":[0.9893749,0.0006265409,0.003389913,0.00007580086,0.00000476814,0.00006414053,0.0003182652,0.00004661239,0.006099015],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005232239,"threshold_uncertainty_score":0.01040357,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01036015913386557,"score_gpt":0.2709496110885537,"score_spread":0.2605894519546881,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}