{"id":"W4318173892","doi":"10.1093/eurheartj/ehac810","title":"Improving representativeness in trials: a call to action from the Global Cardiovascular Clinical Trialists Forum","year":2023,"lang":"en","type":"review","venue":"European Heart Journal","topic":"Sex and Gender in Healthcare","field":"Medicine","cited_by":74,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Joseph’s Healthcare Hamilton; Impact; McMaster University Medical Centre; Population Health Research Institute; McMaster University","funders":"Medical Research Council; National Institutes of Health","keywords":"Representativeness heuristic; Generalizability theory; Medicine; Clinical trial; Randomized controlled trial; Population; Disease; Gerontology; External validity; Call to action; Family medicine; Environmental health; Surgery; Marketing; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":["metaresearch"],"category_scores_codex":[0.7340103,0.00303569,0.01853064,0.006038475,0.005870646,0.02887999,0.01799081,0.05995195,0.0127496],"category_scores_gemma":[0.7379927,0.003676896,0.01140523,0.007683145,0.0365913,0.05384861,0.01882019,0.08928723,0.004177213],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.01754509,"about_ca_system_score_gemma":0.08910104,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005301915,"about_ca_topic_score_gemma":0.006652762,"domain_scores_codex":[0.3549942,0.4903695,0.06072088,0.0174802,0.06950309,0.006932102],"domain_scores_gemma":[0.05894159,0.8434895,0.02013755,0.02022521,0.04101721,0.01618897],"domain_codex":"methods","domain_gemma":"methods","domain_candidate":"methods","domain_consensus":"methods","study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001071537,0.0002698302,0.001538127,0.01790778,0.001236539,0.0003468532,0.006930168,0.0007373889,0.000367096,0.05745815,0.6998264,0.2123102],"study_design_scores_gemma":[0.001612057,0.0008171495,0.002381854,0.05772096,0.0009622317,0.0004478789,0.004444305,0.001751464,0.0003921186,0.1334674,0.7954858,0.0005167581],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0002903984,0.04912753,0.005109773,0.9316881,0.01220297,0.0002952484,0.0001122282,0.0001580425,0.001015705],"genre_scores_gemma":[0.01532417,0.0419244,0.04095605,0.8698593,0.02689198,0.002848525,0.0003050682,0.0004161295,0.001474404],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.2659897,"threshold_uncertainty_score":0.3280128,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.7469419793961861,"score_gpt":0.601916054245585,"score_spread":0.1450259251506011,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}