{"id":"W4318188920","doi":"10.1159/000529336","title":"Epigenetic Mechanisms Governing Female and Male Germline Development in Mammals","year":2022,"lang":"en","type":"review","venue":"Sexual Development","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Biology; Germline; Reprogramming; Epigenome; Epigenetics; Chromatin; H3K4me3; DNA methylation; Histone; Genetics; Somatic cell; Germ cell; Cell biology; Gene; Promoter; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008180667,0.0004941814,0.0007824801,0.0001869312,0.0001869444,0.00004357266,0.0002832028,0.0003231952,0.0002655774],"category_scores_gemma":[0.0000705327,0.0005063669,0.00006885952,0.0001984542,0.00003261428,0.000003152671,0.000691706,0.0002678283,0.00004034144],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002027124,"about_ca_system_score_gemma":0.0009117547,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008546471,"about_ca_topic_score_gemma":0.0001013372,"domain_scores_codex":[0.9971945,0.0001908313,0.0009179915,0.0008771177,0.0003570845,0.0004624967],"domain_scores_gemma":[0.9991401,0.00004191571,0.000320583,0.0003324225,0.0000288161,0.0001360923],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000007028723,0.00006399056,0.00007949687,0.001880813,0.00009996595,0.00002299897,0.0002175688,0.0000124443,0.0005424906,0.00002390961,0.00002277929,0.9970265],"study_design_scores_gemma":[0.0002252636,0.0001033108,0.0002484098,0.0003747842,0.00004148667,0.00002062382,0.00007884679,0.000002118251,0.001741183,0.00001218878,0.9965129,0.0006388556],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.009819149,0.9871844,0.001348455,0.000004323743,0.0002552721,0.0007113627,0.00002177112,0.00001241969,0.0006428228],"genre_scores_gemma":[0.000289037,0.9768189,0.01608062,0.00003111826,0.00008210041,0.0004341198,0.001606984,0.00009042833,0.004566672],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9964901,"threshold_uncertainty_score":0.9997388,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05443646396044032,"score_gpt":0.3122581106595761,"score_spread":0.2578216466991358,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}