{"id":"W4318188920","doi":"10.1159/000529336","title":"Epigenetic Mechanisms Governing Female and Male Germline Development in Mammals","year":2022,"lang":"en","type":"review","venue":"Sexual Development","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Biology; Germline; Reprogramming; Epigenome; Epigenetics; Chromatin; H3K4me3; DNA methylation; Histone; Genetics; Somatic cell; Germ cell; Cell biology; Gene; Promoter; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002155236,0.0001553189,0.0001833951,0.0003050905,0.0002190524,0.0004729354,0.0002785975,0.0003315804,0.001286266],"category_scores_gemma":[0.0001680913,0.000117125,0.0001900649,0.0001764834,0.000432494,0.0003065308,0.0003875763,0.0003375399,0.0004363723],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002673989,"about_ca_system_score_gemma":0.0002180185,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004133431,"about_ca_topic_score_gemma":0.0006687499,"domain_scores_codex":[0.999894,0.00001366048,0.000007250449,0.00004119597,0.00002821231,0.0000156102],"domain_scores_gemma":[0.9999276,0.000009588986,0.00003035875,0.000005338525,0.00001409268,0.00001295216],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001359076,0.00001677543,0.008298697,0.001077972,0.0001180829,0.0009546824,0.0005133967,0.0006361943,0.8429528,0.01678909,0.001577322,0.1269291],"study_design_scores_gemma":[0.0000427075,0.0006110272,0.2667286,0.0005016347,0.0003450628,0.008215008,0.0006770057,0.001624084,0.272365,0.01946697,0.4293087,0.0001141343],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.4000446,0.4647013,0.07247271,0.002112042,0.0005288434,0.0001439855,0.003574229,0.001077753,0.05534465],"genre_scores_gemma":[0.8931652,0.07483386,0.01343013,0.0008972443,0.0002820644,0.00007846708,0.001747476,0.0001066183,0.01545889],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001286266,"threshold_uncertainty_score":0.004302979,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05443646396044032,"score_gpt":0.3122581106595761,"score_spread":0.2578216466991358,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}