{"id":"W4318263338","doi":"10.1084/jem.20222173","title":"Tingible body macrophages arise from lymph node–resident precursors and uptake B cells by dendrites","year":2023,"lang":"en","type":"article","venue":"The Journal of Experimental Medicine","topic":"Phagocytosis and Immune Regulation","field":"Immunology and Microbiology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"European Research Council; Horizon 2020 Framework Programme; Innovative Medicines Initiative; Azrieli Foundation; Israel Science Foundation; European Commission; European Federation of Pharmaceutical Industries and Associations; European Molecular Biology Organization","keywords":"Germinal center; Lymph node; Lymph; Lymph node stromal cell; Biology; Immune system; Cell biology; Bone marrow; Phagocytosis; Antibody; Lymphatic system; Apoptosis; B cell; Immunology; Pathology; Medicine; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004739028,0.0001425481,0.000303191,0.0000946169,0.0001621077,0.00001007981,0.000200248,0.00007914055,0.0007704907],"category_scores_gemma":[0.00004348533,0.00008371911,0.00004880687,0.0001135008,0.0002587694,0.0001042986,0.00008185005,0.0001627008,0.0001001169],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003874719,"about_ca_system_score_gemma":0.00001701484,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002470284,"about_ca_topic_score_gemma":6.435814e-7,"domain_scores_codex":[0.9989889,0.0001783333,0.0004348355,0.0001047664,0.00009212651,0.0002010958],"domain_scores_gemma":[0.9992517,0.0002468017,0.0002844445,0.000145407,0.00003723926,0.00003446625],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002122554,0.00004959861,0.000464998,0.000003472502,0.0001378009,0.000005984134,0.002766191,0.000004192112,0.9560357,0.000008413933,0.03972534,0.0005860315],"study_design_scores_gemma":[0.002221423,0.000357877,0.01081574,0.0001512555,0.00009384692,0.0001033553,0.005309366,0.00002330867,0.9759443,0.00006013988,0.004835499,0.00008387159],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9055797,0.09258504,0.00001683407,0.0007234442,0.0008260719,0.00008578868,0.00001085008,0.00001704754,0.0001552466],"genre_scores_gemma":[0.9957055,0.002447269,0.00001915155,0.0001294888,0.0001273608,0.000002325035,0.0000295001,0.00001483357,0.001524556],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09013777,"threshold_uncertainty_score":0.8436334,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01275622878065764,"score_gpt":0.26679493373243,"score_spread":0.2540387049517723,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}