{"id":"W4318302179","doi":"10.1016/s2352-3026(22)00377-5","title":"Emicizumab in people with moderate or mild haemophilia A (HAVEN 6): a multicentre, open-label, single-arm, phase 3 study","year":2023,"lang":"en","type":"article","venue":"The Lancet Haematology","topic":"Hemophilia Treatment and Research","field":"Medicine","cited_by":83,"is_retracted":false,"has_abstract":false,"ca_institutions":"Memorial University of Newfoundland","funders":"Hospices Civils de Lyon; F. Hoffmann-La Roche","keywords":"Medicine; Open label; Haemophilia; Physical therapy; Pediatrics; Internal medicine; Clinical trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005863159,0.0002724567,0.001384023,0.0002346524,0.0001837844,0.00006079615,0.0005368147,0.0001122351,0.0001901867],"category_scores_gemma":[0.0001759609,0.0001391671,0.0000307306,0.001076102,0.0001650391,0.00009694045,0.0003564708,0.000439319,0.0003633261],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001086469,"about_ca_system_score_gemma":0.0002377638,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003750812,"about_ca_topic_score_gemma":0.004024544,"domain_scores_codex":[0.9975637,0.0003485241,0.0003720019,0.0005070497,0.0003359367,0.0008727392],"domain_scores_gemma":[0.998464,0.0003981143,0.00008702744,0.0008142623,0.0000881654,0.0001484082],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.1987266,0.09189394,0.457869,0.001905498,0.002675481,0.1053754,0.07071621,0.0002228945,0.004425109,0.001238991,0.04939674,0.01555416],"study_design_scores_gemma":[0.7305903,0.05782423,0.05497288,0.002314911,0.001914135,0.0123188,0.03575654,0.08450024,0.009168643,0.002447754,0.005821675,0.002369839],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9769554,0.0001397477,0.000005628193,0.01810333,0.00008114045,0.003323486,0.00001880787,0.0001555354,0.001216913],"genre_scores_gemma":[0.9944611,0.0001232437,0.0002537831,0.0005139896,0.0001084219,0.0004066059,0.00005571978,0.00005119873,0.004025929],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5318637,"threshold_uncertainty_score":0.5675068,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1899997733047888,"score_gpt":0.4239973036752933,"score_spread":0.2339975303705045,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}