{"id":"W4318393621","doi":"10.1080/15548627.2023.2172873","title":"PRKN/parkin-mediated mitophagy is induced by the probiotics <i>Saccharomyces boulardii</i> and <i>Lactococcus lactis</i>","year":2023,"lang":"en","type":"article","venue":"Autophagy","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lallemand (Canada); University of Toronto","funders":"Canadian Institutes of Health Research; Mitacs","keywords":"Mitophagy; Biology; Parkin; Mitochondrion; Autophagy; Saccharomyces boulardii; Cell biology; Probiotic; Pharmacology; Parkinson's disease; Biochemistry; Disease; Genetics; Internal medicine; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001510596,0.0003075988,0.0004379072,0.0001654984,0.0001252765,0.0002402857,0.0001038509,0.0002093634,0.0006874874],"category_scores_gemma":[0.0001126604,0.0001352461,0.0003032523,0.0001171919,0.0001946399,0.0001428418,0.000266905,0.0004520633,0.0001272411],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002295575,"about_ca_system_score_gemma":0.0001734424,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006341176,"about_ca_topic_score_gemma":0.001153278,"domain_scores_codex":[0.9997835,0.00003937941,0.00003036555,0.00004835097,0.00004989988,0.00004849894],"domain_scores_gemma":[0.9998837,0.00001559159,0.00004391671,0.00001037228,0.00001328481,0.00003323259],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001363129,0.00001954877,0.000152953,0.00002294585,0.000003183789,0.0000203284,0.000006583665,0.0000110679,0.9992296,0.000006833438,0.00000944939,0.0003812018],"study_design_scores_gemma":[0.00001408123,0.0005745866,0.009293615,0.000007347785,0.00001369725,0.0001398516,0.00003171058,0.0002345326,0.989089,0.00001142428,0.000586477,0.00000377428],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975927,0.0008679423,0.0007572485,0.0001042713,0.00001554454,0.00001934215,0.0001736759,0.00003297913,0.0004361893],"genre_scores_gemma":[0.9969143,0.0004652389,0.001467203,0.00007904046,0.000006417587,0.00003299793,0.0003429864,0.00001486791,0.0006769545],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006874874,"threshold_uncertainty_score":0.002299845,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01817096082220667,"score_gpt":0.2663026534608565,"score_spread":0.2481316926386498,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}