{"id":"W4318475562","doi":"10.1364/boe.484092","title":"Quantification of structural heterogeneity in H&E stained clear cell renal cell carcinoma using refractive index tomography","year":2023,"lang":"en","type":"article","venue":"Biomedical Optics Express","topic":"Digital Holography and Microscopy","field":"Physics and Astronomy","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Kootenay Association for Science & Technology","funders":"Commercializations Promotion Agency for R and D Outcomes; Korea Health Industry Development Institute; National Research Foundation of Korea; Ministry of Science and ICT, South Korea; Ministry of Health and Welfare; National Research Foundation","keywords":"Clear cell renal cell carcinoma; Pathology; Renal cell carcinoma; Histopathology; Tomography; Medicine; Radiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003903498,0.0002491757,0.0001133713,0.0009008152,0.0001273314,0.0003968208,0.0001956101,0.0003125345,0.0008226215],"category_scores_gemma":[0.0005801194,0.0002185882,0.0001087491,0.0003759653,0.0003466252,0.000449933,0.0002515619,0.0001922596,0.0001436058],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002285474,"about_ca_system_score_gemma":0.0001962537,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009797828,"about_ca_topic_score_gemma":0.00150333,"domain_scores_codex":[0.9998749,0.00002355881,0.000009615385,0.00003131333,0.00004326422,0.00001718216],"domain_scores_gemma":[0.9997013,0.0001034484,0.00008824452,0.0000330059,0.00005229213,0.00002163899],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001633036,0.00002450254,0.009470173,0.00008386587,0.00003007223,0.0002142091,0.0001182303,0.002498916,0.9766998,0.0004563648,0.00009578103,0.01014471],"study_design_scores_gemma":[0.00001809179,0.000174553,0.1117547,0.0000236074,0.000100636,0.001724282,0.000251354,0.07804234,0.8057767,0.0006120196,0.001470204,0.00005162992],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9383597,0.001033626,0.05811188,0.0000868301,0.00001162426,0.00004095263,0.0002993289,0.0003098685,0.001746198],"genre_scores_gemma":[0.9720338,0.0005480733,0.02625267,0.00004532895,0.00001051074,0.00002945052,0.0002434116,0.00004908029,0.0007875549],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009797828,"threshold_uncertainty_score":0.002752006,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02347329981559501,"score_gpt":0.2894910137028981,"score_spread":0.2660177138873031,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}