{"id":"W4318478165","doi":"10.3390/brainsci13020232","title":"Dynamic Amyloid and Metabolic Signatures of Delayed Recall Performance within the Clinical Spectrum of Alzheimer’s Disease","year":2023,"lang":"en","type":"article","venue":"Brain Sciences","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Neurological Institute and Hospital; Center for Diagnosis and Research on Alzheimer's Disease; McGill University; Douglas Mental Health University Institute","funders":"National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; Genentech; National Institutes of Health; H. Lundbeck A/S; Servier; Eisai; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Northern California Institute for Research and Education; F. Hoffmann-La Roche; University of Southern California; Biogen; BioClinica; Novartis Pharmaceuticals Corporation; Pfizer; Eli Lilly and Company; Bristol-Myers Squibb; U.S. Department of Defense; Meso Scale Diagnostics; National Institute on Aging; Consortium canadien en neurodégénérescence associée au vieillissement; Alzheimer's Association; Foundation for the National Institutes of Health","keywords":"Temporal lobe; Dementia; Psychology; Frontal lobe; Neuroimaging; Alzheimer's disease; Recall; Positron emission tomography; Neuroscience; Hippocampus; Neuropsychology; Verbal memory; Cognition; Parietal lobe; Audiology; Disease; Internal medicine; Medicine; Cognitive psychology; Epilepsy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004626402,0.0004082571,0.0002544595,0.0008854796,0.0001792989,0.0004684225,0.0002243729,0.0003278696,0.0007187959],"category_scores_gemma":[0.001052239,0.00016871,0.0001774991,0.0004082785,0.0002171221,0.0002738577,0.0002502765,0.0002884183,0.0001343313],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001611206,"about_ca_system_score_gemma":0.00009405777,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001215774,"about_ca_topic_score_gemma":0.001477149,"domain_scores_codex":[0.9998901,0.00002321702,0.00001420238,0.00003362579,0.00001976949,0.00001910938],"domain_scores_gemma":[0.9993466,0.0001209614,0.0003163558,0.000061764,0.00008353579,0.00007073719],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002171349,0.0001549792,0.9643423,0.00002962669,0.0001467781,0.0007984794,0.0003538542,0.0002615994,0.02181718,0.00007614814,0.00009622071,0.009751569],"study_design_scores_gemma":[0.00001311953,0.0001856795,0.997178,0.000003473188,0.00002647967,0.001084993,0.00009696238,0.0003004558,0.000901855,0.0001212145,0.00008393683,0.000003838624],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9996251,0.00009998937,0.00005486103,0.000006809335,0.000001015339,0.000001541163,0.00003040762,0.000001800756,0.0001784386],"genre_scores_gemma":[0.9997126,0.0000381141,0.00007602945,0.000006034502,0.000004232969,0.000002441438,0.00006901013,0.00000123862,0.00009019883],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001215774,"threshold_uncertainty_score":0.002446711,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04971997462276687,"score_gpt":0.3896161237321148,"score_spread":0.3398961491093479,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}