{"id":"W4318542651","doi":"10.1111/add.16147","title":"Comprehensive needle and syringe program and opioid agonist therapy reduce HIV and hepatitis c virus acquisition among people who inject drugs in different settings: A pooled analysis of emulated trials","year":2023,"lang":"en","type":"review","venue":"Addiction","topic":"HIV, Drug Use, Sexual Risk","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity; British Columbia Centre on Substance Use; Simon Fraser University","funders":"National Institute on Drug Abuse; Rijksinstituut voor Volksgezondheid en Milieu; National Institute of Allergy and Infectious Diseases; Medical Research Council; Stichting Sanquin Bloedvoorziening; National Institutes of Health; Michael Smith Health Research BC; Universiteit van Amsterdam; Center for AIDS Research, University of Washington; Stichting HIV Monitoring; Amsterdam University Medical Centers; National Institute for Health and Care Research; National Institute for Health Research Health Protection Research Unit; St. Paul's Foundation; Burnet Institute","keywords":"Medicine; Cohort; Syringe; Hepatitis C; Harm reduction; Cohort study; Internal medicine; Drug injection; Hepatitis C virus; Hazard ratio; Drug; Human immunodeficiency virus (HIV); Pharmacology; Virology; Confidence interval; Virus; Psychiatry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005909613,0.0005228381,0.004132831,0.00135613,0.0001116594,0.00008880049,0.00006829445,0.0004039998,0.00002290683],"category_scores_gemma":[0.000212787,0.0004150001,0.0003160702,0.001811253,0.0001455489,0.0001213584,0.00009133742,0.0004057794,0.000002295099],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001573089,"about_ca_system_score_gemma":0.00007541265,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002628914,"about_ca_topic_score_gemma":0.0005897419,"domain_scores_codex":[0.996592,0.0007217586,0.001333458,0.0007020337,0.0003546819,0.0002961025],"domain_scores_gemma":[0.9976003,0.0008044053,0.0009411313,0.0003405215,0.0001507551,0.000162945],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.0002311679,0.0002482307,0.009092999,0.006346118,0.005296643,0.00001494943,0.01144895,0.000004496782,0.0001639401,0.000002013908,0.000230639,0.9669198],"study_design_scores_gemma":[0.01027722,0.00332508,0.8166906,0.05278658,0.06360195,0.00008825114,0.008686387,0.01055999,0.0002104599,0.00003655749,0.03189799,0.001838891],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.5672467,0.4296924,0.000003998416,0.0000249905,0.00006775938,0.002453254,0.0003825806,0.0001141399,0.00001419896],"genre_scores_gemma":[0.0692476,0.92711,0.00003869305,0.00002047987,0.0001271205,0.0004394481,0.002865119,0.000075881,0.000075641],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.965081,"threshold_uncertainty_score":0.9998302,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06020842692986861,"score_gpt":0.3809794790220472,"score_spread":0.3207710520921785,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}