{"id":"W4318577437","doi":"10.1093/ecco-jcc/jjac190.0801","title":"P671 Ustekinumab in paediatric patients with moderately to severely active Crohn's disease: Results from the UniStar study long-term extension","year":2023,"lang":"en","type":"article","venue":"Journal of Crohn s and Colitis","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"Medicine; Ustekinumab; Dosing; Internal medicine; Gastroenterology; Adverse effect; Pediatrics; Surgery; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00374111,0.0007298535,0.001751139,0.0002460019,0.0003387967,0.0007768617,0.0005283767,0.0006962598,0.001303513],"category_scores_gemma":[0.002177473,0.0003459657,0.001656163,0.0005346605,0.0006099606,0.0007929448,0.0006969761,0.001812863,0.0003901809],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006908818,"about_ca_system_score_gemma":0.001221233,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008797299,"about_ca_topic_score_gemma":0.001395703,"domain_scores_codex":[0.9982754,0.0009933847,0.0001619807,0.000183427,0.0002305304,0.0001552918],"domain_scores_gemma":[0.9971935,0.0004449665,0.001124538,0.0002198755,0.0002664066,0.0007506714],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.7563571,0.01842014,0.09449751,0.003251245,0.00394271,0.0005567124,0.0006635609,0.001191343,0.01744238,0.0002004765,0.003515341,0.09996143],"study_design_scores_gemma":[0.1540321,0.5486863,0.2828943,0.0002249045,0.003011874,0.001176143,0.0001946754,0.0005926908,0.002829682,0.0001032303,0.006186608,0.00006759578],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9851878,0.01151081,0.0001992977,0.0001709667,0.00005119515,0.0007251281,0.001188045,0.00002401953,0.0009426702],"genre_scores_gemma":[0.9925032,0.003682555,0.0005783871,0.0002651995,0.0001651135,0.0004624406,0.00184106,0.000009762927,0.0004923446],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00374111,"threshold_uncertainty_score":0.01978517,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009341811045465545,"score_gpt":0.2393557253403164,"score_spread":0.2300139142948509,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}