{"id":"W4318578768","doi":"10.1093/ecco-jcc/jjac190.0776","title":"P646 Relative association of bowel urgency clinically meaningful improvement and bowel urgency remission versus stool frequency remission and rectal bleeding remission with improvement in Work Productivity and Activity Impairment Scores in patients with moderately-to-severely active Ulcerative Colitis: An analysis from LUCENT-1 and LUCENT-2 Phase 3 clinical trials.","year":2023,"lang":"en","type":"article","venue":"Journal of Crohn s and Colitis","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Absenteeism; Medicine; Confounding; Presenteeism; Internal medicine; Ulcerative colitis; Physical therapy; Psychology; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007701807,0.0007581497,0.002967209,0.0003998657,0.0004872062,0.001441049,0.000799485,0.001456643,0.005500083],"category_scores_gemma":[0.008926027,0.0004574762,0.005034802,0.001147361,0.000897315,0.001388642,0.0005431654,0.003392655,0.0004980559],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005663791,"about_ca_system_score_gemma":0.0008991808,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006197359,"about_ca_topic_score_gemma":0.001577189,"domain_scores_codex":[0.9958014,0.002625672,0.0004058506,0.0005328064,0.0003573681,0.0002769776],"domain_scores_gemma":[0.9935784,0.003466993,0.001875096,0.0003259797,0.0002857503,0.0004677143],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.8468124,0.002261986,0.03933148,0.007667965,0.03886478,0.0001792004,0.0001420843,0.0008585834,0.002054412,0.0003484269,0.003225618,0.05825317],"study_design_scores_gemma":[0.5447323,0.1558699,0.2058885,0.001125611,0.07736918,0.0005830593,0.0001863029,0.00318557,0.0015109,0.002325895,0.007070255,0.0001524241],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8881832,0.09835727,0.001382773,0.002360529,0.0006919657,0.001526587,0.00324391,0.0001193995,0.004134354],"genre_scores_gemma":[0.9899856,0.005412844,0.0005623898,0.0008314786,0.0004353519,0.000780496,0.00114747,0.00001698262,0.0008275358],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007701807,"threshold_uncertainty_score":0.04073149,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02170586615409932,"score_gpt":0.3248240490517812,"score_spread":0.3031181828976819,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}