{"id":"W4318613885","doi":"10.1210/endocr/bqad017","title":"Follistatin Forms a Stable Complex With Inhibin A That Does Not Interfere With Activin A Antagonism","year":2023,"lang":"en","type":"article","venue":"Endocrinology","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Basic Energy Sciences; National Health and Medical Research Council; Lawrence Berkeley National Laboratory; National Institute of General Medical Sciences; Medical Research Council; Canadian Institutes of Health Research; National Institutes of Health; U.S. Department of Energy","keywords":"Follistatin; Antagonism; Endocrinology; Internal medicine; Activin receptor; Chemistry; Biology; Medicine; Receptor; Transforming growth factor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002103739,0.0003821237,0.0004126185,0.0002804189,0.0003028325,0.0005523633,0.0005912061,0.000535575,0.001579988],"category_scores_gemma":[0.0004077814,0.0002634733,0.0003704154,0.0001980369,0.0002452602,0.000269286,0.0003111229,0.0007325107,0.0007379154],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007149673,"about_ca_system_score_gemma":0.0003488657,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001077527,"about_ca_topic_score_gemma":0.001252799,"domain_scores_codex":[0.9994889,0.00005821232,0.00004949668,0.000151063,0.0001581213,0.00009417792],"domain_scores_gemma":[0.9997715,0.00003766107,0.00005253153,0.00003828141,0.00004074433,0.00005926692],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001326325,0.00006551763,0.0003747913,0.00003198268,0.00003549378,0.00005925198,0.00002699601,0.0001303774,0.9975805,0.0001243126,0.0001252433,0.001312923],"study_design_scores_gemma":[0.00003308846,0.0001116822,0.002449635,0.000005082145,0.00002018195,0.0002055199,0.00002352227,0.001872878,0.9901199,0.000049969,0.005100709,0.000007909548],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9883094,0.001799077,0.006438697,0.0001516633,0.00009222401,0.00007342908,0.0003275783,0.0001672808,0.002640637],"genre_scores_gemma":[0.9873176,0.0004459422,0.004450762,0.00013895,0.00001436599,0.00005427955,0.001497554,0.00005349697,0.006027011],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001579988,"threshold_uncertainty_score":0.005285621,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02431789857175807,"score_gpt":0.2659640326549474,"score_spread":0.2416461340831894,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}