{"id":"W4318677259","doi":"10.1016/j.biopsych.2023.01.018","title":"Alcohol Dependence Modifies Brain Networks Activated During Withdrawal and Reaccess: A c-Fos–Based Analysis in Mice","year":2023,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Neurotransmitter Receptor Influence on Behavior","field":"Neuroscience","cited_by":64,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill; National Institutes of Health; National Cancer Institute; National Institute of Mental Health; National Institute on Alcohol Abuse and Alcoholism; U.S. Department of Veterans Affairs","keywords":"c-Fos; Neuroscience; Psychology; Alcohol dependence; Alcohol; Biology; Gene expression; Genetics; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002578284,0.0002929396,0.0003769239,0.0004750699,0.000181516,0.0001033092,0.0005074923,0.0002429285,0.00007068829],"category_scores_gemma":[0.0002277147,0.0002342494,0.0001429325,0.003231656,0.0002699608,0.0002241944,0.0001194264,0.0004831158,0.00003667415],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003080719,"about_ca_system_score_gemma":0.00003279118,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004852321,"about_ca_topic_score_gemma":0.00006816364,"domain_scores_codex":[0.9972995,0.0003696247,0.0004136626,0.001047627,0.0002616376,0.0006079352],"domain_scores_gemma":[0.9990188,0.0003575688,0.0001292032,0.0003214789,0.00001763082,0.0001552689],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001785035,0.00009842513,0.4263704,0.00001214088,0.000009928835,0.00005947068,0.00003162646,0.001700897,0.5711246,0.00005585635,0.00004460086,0.0003135642],"study_design_scores_gemma":[0.001041017,0.0001202344,0.9281526,0.00004115675,0.00004360017,0.00001670476,0.00004734827,0.004665,0.06521102,0.0001988293,0.00002819892,0.0004343234],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973032,0.00004430143,0.0001256474,0.001381442,0.0002967356,0.0003809417,0.00002012999,0.0003843437,0.00006328707],"genre_scores_gemma":[0.9981672,0.00004898024,0.0001861464,0.001372937,0.00005906932,0.00009413422,0.000008700071,0.00001980842,0.00004304435],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5059135,"threshold_uncertainty_score":0.9552414,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05039708385931503,"score_gpt":0.3133153363195081,"score_spread":0.2629182524601931,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}