{"id":"W4318679019","doi":"10.1016/j.ekir.2023.01.029","title":"Increasing Serum Bicarbonate is Associated With Reduced Risk of Adverse Kidney Outcomes in Patients with CKD and Metabolic Acidosis","year":2023,"lang":"en","type":"article","venue":"Kidney International Reports","topic":"Renal function and acid-base balance","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Seven Oaks General Hospital","funders":"Netherlands Leprosy Relief; Fondation Sanofi Espoir","keywords":"Medicine; Kidney disease; Internal medicine; Renal function; Dialysis; Metabolic acidosis; Bicarbonate; Hazard ratio; Proportional hazards model; Confidence interval","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003930809,0.0001785155,0.0004054923,0.0003796708,0.00003836558,0.0000104309,0.00005201778,0.00006892208,0.0001152572],"category_scores_gemma":[0.003966605,0.0001253161,0.00006757766,0.0004916743,0.00006626746,0.0001485257,0.0000447376,0.0001744736,0.000004930696],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007511508,"about_ca_system_score_gemma":0.0002513364,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003193308,"about_ca_topic_score_gemma":0.00001130125,"domain_scores_codex":[0.9982268,0.00005516507,0.0004640027,0.0003403976,0.0007222446,0.0001913502],"domain_scores_gemma":[0.9985309,0.00008279822,0.0005158505,0.0002191954,0.0003466745,0.0003045514],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004856142,0.0001701502,0.9961198,0.0000165532,0.0005833585,0.0002006411,0.0001259798,0.00001069137,0.001167872,0.00001286235,0.0008337551,0.0002727229],"study_design_scores_gemma":[0.002930386,0.0001209578,0.9895312,0.0004856379,0.0001594787,0.00005580622,0.00003352389,0.0002145933,0.004951478,0.00004073589,0.001341848,0.0001343163],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958305,0.000008849473,0.000003670696,0.001814783,0.0002613891,0.0002734596,0.0001901248,0.00006825023,0.00154901],"genre_scores_gemma":[0.996777,0.0000459502,0.00018755,0.001348331,0.0000244658,0.00001932815,0.000339378,0.0000253985,0.001232619],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006588563,"threshold_uncertainty_score":0.5110241,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006606654030096661,"score_gpt":0.2379808243167224,"score_spread":0.2313741702866257,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}