{"id":"W4318685191","doi":"10.5853/jos.2022.02453","title":"The Rescue on Reperfusion Damage in Cerebral Infarction by Nelonemdaz (RODIN) Trial: Protocol for a Double-Blinded Clinical Trial of Nelonemdaz in Patients with Hyperacute Ischemic Stroke and Endovascular Thrombectomy","year":2023,"lang":"en","type":"article","venue":"Journal of Stroke","topic":"Acute Ischemic Stroke Management","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Modified Rankin Scale; Stroke (engine); Clinical endpoint; Clinical trial; Cerebral infarction; Placebo; Internal medicine; Anesthesia; Ischemia; Ischemic stroke; Pathology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003007975,0.0002906963,0.0009558289,0.000491994,0.00008647617,0.00004469099,0.0002547733,0.0002232402,0.00001719481],"category_scores_gemma":[0.0005845725,0.0001827592,0.0003236955,0.0004404093,0.0001517951,0.0002272859,0.0001345799,0.0008949416,0.000002019656],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001663124,"about_ca_system_score_gemma":0.000207765,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004546027,"about_ca_topic_score_gemma":0.00002879442,"domain_scores_codex":[0.9960317,0.0001892635,0.001916049,0.0003955169,0.001040703,0.0004267567],"domain_scores_gemma":[0.9976288,0.0004571977,0.0009885064,0.0004819125,0.0002932813,0.0001503225],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9094279,0.001461702,0.05293025,0.0001225402,0.0004408288,0.00002754712,0.0001363296,0.00003228608,0.003095441,0.000009608378,0.02765489,0.004660657],"study_design_scores_gemma":[0.8917051,0.01653281,0.06376589,0.0005505617,0.0002486075,0.00001057808,0.0003252703,0.000264478,0.004298509,0.000005007867,0.02209398,0.000199186],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9302583,0.000008409896,0.0000284042,0.0009784405,0.000295516,0.06794639,0.00002432396,0.00001784626,0.0004423852],"genre_scores_gemma":[0.973344,0.0001067475,0.0016323,0.0002348371,0.0008972597,0.0218762,0.00005089664,0.0001093977,0.001748367],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0460702,"threshold_uncertainty_score":0.7452704,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05165857834847672,"score_gpt":0.3621925236021755,"score_spread":0.3105339452536988,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}