{"id":"W4318685191","doi":"10.5853/jos.2022.02453","title":"The Rescue on Reperfusion Damage in Cerebral Infarction by Nelonemdaz (RODIN) Trial: Protocol for a Double-Blinded Clinical Trial of Nelonemdaz in Patients with Hyperacute Ischemic Stroke and Endovascular Thrombectomy","year":2023,"lang":"en","type":"article","venue":"Journal of Stroke","topic":"Acute Ischemic Stroke Management","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Modified Rankin Scale; Stroke (engine); Clinical endpoint; Clinical trial; Cerebral infarction; Placebo; Internal medicine; Anesthesia; Ischemia; Ischemic stroke; Pathology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008901934,0.003997365,0.005315525,0.0007473091,0.002016899,0.001912729,0.002146387,0.004763801,0.02297747],"category_scores_gemma":[0.007255338,0.00150322,0.002048902,0.0008045507,0.002167764,0.00158346,0.0009032974,0.004173148,0.005111411],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001973711,"about_ca_system_score_gemma":0.005375265,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001088053,"about_ca_topic_score_gemma":0.002832167,"domain_scores_codex":[0.9952035,0.002855902,0.0003441261,0.0006339746,0.0003528782,0.0006096371],"domain_scores_gemma":[0.9964541,0.000485634,0.0008396499,0.0005464871,0.000467291,0.001206813],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9787742,0.005771791,0.0004543863,0.00100178,0.0003193227,0.00008779968,0.00007585136,0.0004275837,0.002175188,0.000500546,0.005206001,0.005205373],"study_design_scores_gemma":[0.9783039,0.01557262,0.0007951873,0.0001023747,0.0001255032,0.00003228928,0.00001384342,0.0003559572,0.0002780275,0.0002705958,0.004123955,0.00002567163],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.06724375,0.001103783,0.002821476,0.001470292,0.001238893,0.9151188,0.00588001,0.0003058447,0.004817143],"genre_scores_gemma":[0.0632193,0.0006525207,0.004099291,0.001560207,0.0005021367,0.9239677,0.002129055,0.00003007575,0.003839806],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.02297747,"threshold_uncertainty_score":0.07686728,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05165857834847672,"score_gpt":0.3621925236021755,"score_spread":0.3105339452536988,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}