{"id":"W4318691763","doi":"10.1248/bpb.b22-00631","title":"<i>In Vivo</i> Proof of Biological Safety and Physiological Effects of Orally Ingested Water Containing H<sub>2</sub>-Filled Ultrafine Bubbles (UFBs)","year":2023,"lang":"en","type":"article","venue":"Biological and Pharmaceutical Bulletin","topic":"Hydrogen's biological and therapeutic effects","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Society of Intestinal Research","funders":"Kobe Gakuin University","keywords":"Biological effect; In vivo; Biological activity; Water intake; Food science; Chemistry; Biological safety; Water consumption; Pharmacology; Physiology; Toxicology; Medicine; Biology; Biochemistry; Environmental science; Biotechnology; Environmental engineering; Endocrinology; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001964137,0.0008801459,0.002382348,0.000224402,0.0001997256,0.0000260516,0.0003640389,0.001201499,0.001087782],"category_scores_gemma":[0.001492281,0.0004575477,0.0004057583,0.0006319914,0.001929133,0.00003964023,0.0006007979,0.0007892898,0.0000940364],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005219544,"about_ca_system_score_gemma":0.00004326284,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000033882,"about_ca_topic_score_gemma":0.000002686648,"domain_scores_codex":[0.9938241,0.001408062,0.001461942,0.001389925,0.0004680849,0.001447924],"domain_scores_gemma":[0.9953138,0.003108794,0.0002697335,0.0003586414,0.0001982203,0.0007508024],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.007322516,0.001114197,0.004836453,0.0005757809,0.0002664526,0.0003735543,0.0001202093,0.00001277632,0.9712346,0.001820658,0.0002136997,0.01210908],"study_design_scores_gemma":[0.01279359,0.01289244,0.08405489,0.0008196029,0.00030683,0.0001731293,0.00003551829,0.001006843,0.7975801,0.001535932,0.08759472,0.001206357],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9893388,0.004650119,0.0000498738,0.002851944,0.0001723279,0.001957226,0.00009022694,0.000241561,0.000647925],"genre_scores_gemma":[0.9906272,0.007181659,0.0001874883,0.001267819,0.0002329532,0.0001539936,0.0001954666,0.00003701194,0.0001163996],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1736545,"threshold_uncertainty_score":0.9998254,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04280480132977173,"score_gpt":0.296616824626684,"score_spread":0.2538120232969123,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}