{"id":"W4318701286","doi":"10.32920/21982925.v1","title":"Phagosome resolution regenerates lysosomes and maintains the degradative capacity in phagocytes","year":2023,"lang":"en","type":"preprint","venue":"","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canada Research Chairs; Canadian Institutes of Health Research; Government of Ontario","keywords":"Phagosome; Phagocytosis; Cell biology; Lysosome; Endocytosis; Exocytosis; Biology; Chemistry; Biochemistry; Membrane; Cell; Enzyme","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003474516,0.0002794133,0.0004487111,0.0004753305,0.0003610353,0.0008224298,0.0002671461,0.0006516404,0.0008517449],"category_scores_gemma":[0.0002773609,0.000194813,0.0004217346,0.0002298098,0.0005389153,0.0004899078,0.0008027534,0.0006655729,0.0007675235],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005654772,"about_ca_system_score_gemma":0.0005736617,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006826196,"about_ca_topic_score_gemma":0.00064148,"domain_scores_codex":[0.9997436,0.00002993941,0.000014671,0.00004865878,0.00009259449,0.00007047032],"domain_scores_gemma":[0.9998038,0.00001550574,0.00003849194,0.0000410168,0.0000366862,0.00006442088],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00021061,0.00002740662,0.001108062,0.00007850095,0.00001538937,0.000532208,0.00006141077,0.000348265,0.9902653,0.001968426,0.0003440599,0.005040387],"study_design_scores_gemma":[0.0000274384,0.0001059377,0.01090001,0.00001934332,0.0000163795,0.001327135,0.00009587359,0.00432037,0.9732268,0.002188413,0.007757712,0.00001454077],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.9603479,0.006373953,0.0264199,0.0007621613,0.000169442,0.00003115513,0.00032407,0.0004802428,0.005091169],"genre_scores_gemma":[0.9832786,0.001286367,0.007469713,0.0001116666,0.00004378669,0.0000208881,0.0003762952,0.0001204481,0.007292204],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.0008517449,"threshold_uncertainty_score":0.004102886,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05339195705253304,"score_gpt":0.2528810827083348,"score_spread":0.1994891256558017,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}