{"id":"W4318716869","doi":"10.32920/21982907","title":"pH of endophagosomes controls association of their membranes with Vps34 and PtdIns(3)P levels","year":2023,"lang":"en","type":"preprint","venue":"","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; Toronto Metropolitan University; The Scarborough Hospital; University of Toronto","funders":"University of Toronto Scarborough; University of Toronto; Canadian Institutes of Health Research; Government of Ontario","keywords":"Endosome; Phagosome; Phosphatidylinositol; Cell biology; Phagocytosis; Organelle; Chemistry; Biology; Kinase; Intracellular","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001066547,0.0001767984,0.0001630267,0.0001560222,0.0001102812,0.0005260176,0.0001869395,0.0002853519,0.001619061],"category_scores_gemma":[0.0002330474,0.0002101037,0.0001525413,0.0001182023,0.0002117646,0.0003340871,0.0003603045,0.0003117432,0.0008476304],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005431261,"about_ca_system_score_gemma":0.0001432712,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005473053,"about_ca_topic_score_gemma":0.0003662919,"domain_scores_codex":[0.9998747,0.00001315774,0.000005718563,0.00003864802,0.0000278978,0.00003980011],"domain_scores_gemma":[0.9998994,0.00001908348,0.00002537784,0.00001105607,0.00001132273,0.00003378886],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001355462,0.000006342204,0.0003321045,0.000009747363,0.000001851331,0.00003376229,0.00001101595,0.00005612656,0.9984548,0.0002130504,0.00004212919,0.000703415],"study_design_scores_gemma":[0.00001452698,0.00003799178,0.02008908,0.0000041227,0.000004547664,0.000179259,0.0000334476,0.003096128,0.9750182,0.0002614328,0.001253814,0.000007506231],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950531,0.0005346641,0.002057567,0.00006538556,0.00001992328,0.000006242433,0.0002393055,0.00009492796,0.001928904],"genre_scores_gemma":[0.9964592,0.0002240545,0.0009706761,0.00002599173,0.0000046916,0.00000792409,0.0002903875,0.00004922087,0.001967961],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001619061,"threshold_uncertainty_score":0.005416334,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01696943325726133,"score_gpt":0.2258001979165032,"score_spread":0.2088307646592419,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}