{"id":"W4318753993","doi":"10.1080/10985549.2023.2166320","title":"Sumoylation is Largely Dispensable for Normal Growth but Facilitates Heat Tolerance in Yeast","year":2023,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"SUMO protein; Biology; Cell biology; Mutant; Heat shock protein; Saccharomyces cerevisiae; Heat shock; Yeast; Biochemistry; Ubiquitin; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008702086,0.0002804839,0.0002280705,0.0001694187,0.0001734874,0.0004377784,0.0001837632,0.0001370624,0.0006914476],"category_scores_gemma":[0.0001119977,0.0001573713,0.0001779995,0.0001844049,0.0002387185,0.0001722067,0.0003612837,0.0002446738,0.0004743517],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002064272,"about_ca_system_score_gemma":0.0001643484,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000591943,"about_ca_topic_score_gemma":0.0007661435,"domain_scores_codex":[0.9999328,0.000008089283,0.000009346632,0.00001696218,0.00002119406,0.00001161658],"domain_scores_gemma":[0.9998497,0.00002039871,0.00003628578,0.00002730578,0.00001572041,0.00005066261],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009272298,0.00000677557,0.0004077762,0.00002200584,0.000003630913,0.00007584274,0.000006966272,0.00007824226,0.9980273,0.00008521034,0.00002129438,0.001172275],"study_design_scores_gemma":[0.00001283497,0.0001302198,0.01873085,0.000008661269,0.00001470495,0.0005828699,0.00004016145,0.0009846456,0.9763837,0.000257757,0.002843112,0.00001049871],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945251,0.001226281,0.002736309,0.00005414672,0.00001537193,0.000006546865,0.0004765723,0.0001184691,0.0008412033],"genre_scores_gemma":[0.9970481,0.000461078,0.0009151368,0.00001943162,0.000005088007,0.000005314336,0.0005649743,0.00003224419,0.0009486391],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006914476,"threshold_uncertainty_score":0.002313137,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01254105559762175,"score_gpt":0.2360364781515289,"score_spread":0.2234954225539072,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}