{"id":"W4318754879","doi":"10.1021/acs.jproteome.2c00557","title":"SUMO Proteomics Analyses Identify Protein Inhibitor of Activated STAT-Mediated Regulatory Networks Involved in Cell Cycle and Cell Proliferation","year":2023,"lang":"en","type":"article","venue":"Journal of Proteome Research","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Fonds de recherche du Québec – Nature et technologies; Natural Sciences and Engineering Research Council of Canada; Genome Canada; Canadian Institutes of Health Research; Fonds Québécois de la Recherche sur la Nature et les Technologies; Canada Foundation for Innovation","keywords":"SUMO protein; Cell growth; Cell cycle; Cell biology; Biology; Ubiquitin ligase; Ubiquitin; Proteomics; Cell; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001119795,0.0003045157,0.0002134455,0.000450796,0.0002179002,0.0003029231,0.0001520688,0.0002312153,0.0009842531],"category_scores_gemma":[0.00008772616,0.0001312006,0.0003019771,0.0004363856,0.0001416201,0.0001967199,0.0001320132,0.0002420062,0.0004111022],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003431608,"about_ca_system_score_gemma":0.0002169206,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004324268,"about_ca_topic_score_gemma":0.0008257547,"domain_scores_codex":[0.9999011,0.000006421223,0.000005512913,0.00003248092,0.00003440262,0.00002016011],"domain_scores_gemma":[0.9999348,0.000006386676,0.00002553708,0.000004882445,0.00001282044,0.00001559453],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000127934,0.00001484397,0.001332398,0.00005592122,0.00001301591,0.0000590465,0.00001220593,0.0001083511,0.9961587,0.0001613357,0.00008251925,0.001873703],"study_design_scores_gemma":[0.00002225486,0.0001610767,0.09977881,0.00001002556,0.00006027866,0.0005056345,0.00007054478,0.005567148,0.8875276,0.0003562197,0.005928686,0.00001172258],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9846917,0.003157605,0.007687985,0.00009667792,0.00003594403,0.0000388892,0.002159473,0.000159526,0.001972206],"genre_scores_gemma":[0.9880611,0.001497914,0.004794495,0.00009505804,0.00001157607,0.00004869892,0.002622687,0.00002482766,0.002843553],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009842531,"threshold_uncertainty_score":0.00329262,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05894274951100255,"score_gpt":0.3607917028471938,"score_spread":0.3018489533361913,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}