{"id":"W4318755003","doi":"10.1093/infdis/jiad024","title":"Safety and Immunogenicity of an Investigational Respiratory Syncytial Virus Vaccine (RSVPreF3) in Mothers and Their Infants: A Phase 2 Randomized Trial","year":2023,"lang":"en","type":"article","venue":"The Journal of Infectious Diseases","topic":"Respiratory viral infections research","field":"Medicine","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"Nova Scotia Health Authority; Izaak Walton Killam Health Centre; Dalhousie University","funders":"GlaxoSmithKline Biologicals; GlaxoSmithKline","keywords":"Medicine; Immunogenicity; Placebo; Vaccination; Adverse effect; Pregnancy; Randomized controlled trial; Titer; Immunology; Immune system; Internal medicine; Antibody; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003686205,0.001243998,0.001734124,0.0002611268,0.0003196967,0.0006572009,0.0007638497,0.001693962,0.003452706],"category_scores_gemma":[0.00274433,0.0005152271,0.001183828,0.0002740776,0.0008174703,0.0006509715,0.0002772699,0.001515936,0.0004528936],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005697536,"about_ca_system_score_gemma":0.001317213,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000341331,"about_ca_topic_score_gemma":0.0005938567,"domain_scores_codex":[0.9988133,0.0008294283,0.00006214091,0.0001287406,0.00007826417,0.00008819927],"domain_scores_gemma":[0.9988404,0.0003890664,0.0003590561,0.00009663068,0.0000853503,0.0002295104],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9720891,0.006515495,0.0008471675,0.0005744926,0.0004793103,0.00004764887,0.0000491474,0.0001129367,0.003576499,0.00006313396,0.0003663213,0.01527876],"study_design_scores_gemma":[0.8487445,0.1476731,0.001559447,0.0000404949,0.0003801147,0.0000496703,0.00001799866,0.0002207343,0.0006958624,0.00006718437,0.0005433868,0.000007483848],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9881772,0.004659821,0.0007461034,0.0005756754,0.0003093496,0.004105479,0.0005113301,0.00007975135,0.0008353723],"genre_scores_gemma":[0.9828131,0.004024509,0.002050096,0.0008127082,0.0003385541,0.007819264,0.0005366145,0.00002026525,0.00158486],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003686205,"threshold_uncertainty_score":0.01949477,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02677778898463328,"score_gpt":0.3511928449254645,"score_spread":0.3244150559408313,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}