{"id":"W4318777481","doi":"10.3390/cells12030466","title":"Immune Cells Release MicroRNA-155 Enriched Extracellular Vesicles That Promote HIV-1 Infection","year":2023,"lang":"en","type":"article","venue":"Cells","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; Fondation CHU de Québec; National Institutes of Health; Thomas Jefferson University","keywords":"Peripheral blood mononuclear cell; Viral replication; Immune system; Biology; Microvesicles; microRNA; Autocrine signalling; Inflammation; Immunology; Virology; In vitro; Virus; Cell culture; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004506479,0.0003705687,0.00026215,0.0001331681,0.0001858568,0.00008226026,0.0003855341,0.0003246747,0.0001320129],"category_scores_gemma":[0.00006463023,0.0003976025,0.0003024698,0.0003550562,0.0001590986,0.00001549665,0.0002878991,0.0002277255,0.001913678],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004010212,"about_ca_system_score_gemma":0.00009629091,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002002881,"about_ca_topic_score_gemma":0.000004360451,"domain_scores_codex":[0.9977736,0.000171922,0.0004058146,0.0007506125,0.0002668274,0.0006311767],"domain_scores_gemma":[0.9984249,0.00002845181,0.0002036447,0.0009964041,0.00008501823,0.0002615105],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007468264,0.0001796112,0.0006136883,0.00009676319,0.00006426608,0.0001199778,0.0000861717,0.0002695975,0.9847436,0.0000233652,0.01149128,0.00223697],"study_design_scores_gemma":[0.0006611166,0.0001033064,0.001749584,0.00002464598,0.00006014615,0.00001405007,0.00004866399,0.0003123362,0.9191738,0.0001455973,0.07726985,0.0004369511],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924928,0.00366772,0.001652956,0.0001374625,0.0006843913,0.0005212394,0.00005570403,0.0001903631,0.0005973738],"genre_scores_gemma":[0.9827765,0.001088817,0.0006614763,0.00009261818,0.0003774209,0.00005184534,0.0005333207,0.0001149874,0.01430303],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06577857,"threshold_uncertainty_score":0.9998476,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01110632049788622,"score_gpt":0.2324122629842977,"score_spread":0.2213059424864115,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}