{"id":"W4318920665","doi":"10.1242/dmm.049750","title":"A hepatoprotective role of peritumoral non-parenchymal cells in early liver tumorigenesis","year":2023,"lang":"en","type":"article","venue":"Disease Models & Mechanisms","topic":"Liver physiology and pathology","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Stemcell Technologies","funders":"St. Jude Children's Research Hospital; American Cancer Society","keywords":"Carcinogenesis; Hepatic stellate cell; Parenchyma; Spheroid; In vitro; Liver cancer; Cancer research; Liver tumor; Pathology; Biology; Liver parenchyma; Medicine; Cancer; Internal medicine; Hepatocellular carcinoma; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001230291,0.0002160275,0.0001458975,0.0001923973,0.0001085782,0.0002053974,0.00005776689,0.0001193223,0.0008777124],"category_scores_gemma":[0.00005743988,0.00005810546,0.0001499713,0.0001082816,0.0001604216,0.0001489283,0.0001618259,0.0002588444,0.0001637098],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009789839,"about_ca_system_score_gemma":0.0001456539,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003405217,"about_ca_topic_score_gemma":0.0007028915,"domain_scores_codex":[0.9999322,0.00001801819,0.000006164913,0.00001067295,0.00001999885,0.00001285411],"domain_scores_gemma":[0.999934,0.00001490152,0.00001208094,0.00001389846,0.000008002571,0.00001726498],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000115407,0.00002082922,0.0008555396,0.000057352,0.000004129817,0.00009202704,0.00003438563,0.0000674176,0.9956079,0.0001171864,0.00002563356,0.003002173],"study_design_scores_gemma":[0.000006551988,0.0004226866,0.01202041,0.00000798065,0.00001356573,0.0003687103,0.0000693108,0.0003552013,0.983838,0.00006759806,0.002827108,0.000002830418],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9856623,0.004892134,0.006558722,0.00009595522,0.0000285838,0.00003266802,0.000276889,0.00009761866,0.002355199],"genre_scores_gemma":[0.9957345,0.001262667,0.001494162,0.00003102898,0.000008102256,0.00001632778,0.0002175112,0.000009222707,0.001226485],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008777124,"threshold_uncertainty_score":0.002936244,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01730378614014408,"score_gpt":0.2335730271823196,"score_spread":0.2162692410421755,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}