{"id":"W4318920665","doi":"10.1242/dmm.049750","title":"A hepatoprotective role of peritumoral non-parenchymal cells in early liver tumorigenesis","year":2023,"lang":"en","type":"article","venue":"Disease Models & Mechanisms","topic":"Liver physiology and pathology","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Stemcell Technologies","funders":"St. Jude Children's Research Hospital; American Cancer Society","keywords":"Carcinogenesis; Hepatic stellate cell; Parenchyma; Spheroid; In vitro; Liver cancer; Cancer research; Liver tumor; Pathology; Biology; Liver parenchyma; Medicine; Cancer; Internal medicine; Hepatocellular carcinoma; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001736202,0.0001978624,0.0004271747,0.0002556807,0.00005530239,0.000004475238,0.0001349059,0.0001173157,0.00007321055],"category_scores_gemma":[0.00001454404,0.0001869234,0.0001623113,0.0003736653,0.00007907747,0.0001175942,0.000106479,0.0001847295,0.0001463639],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003902672,"about_ca_system_score_gemma":0.0001752162,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003436637,"about_ca_topic_score_gemma":0.00001141066,"domain_scores_codex":[0.9986075,0.0001007268,0.0002539814,0.0004284527,0.0002228726,0.0003864681],"domain_scores_gemma":[0.999236,0.00003222516,0.00007306621,0.0003390907,0.00009236333,0.0002272063],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.003523167,0.001092062,0.01193965,0.0004404659,0.0001421895,0.00360951,0.009887449,0.00295343,0.9431146,0.02179501,0.00005739336,0.001445104],"study_design_scores_gemma":[0.002654258,0.001089161,0.3236461,0.0002290439,0.00028133,0.00001999477,0.0008737101,0.1973462,0.2376739,0.2356668,0.000008150454,0.0005113985],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965582,0.000141947,0.002118346,0.00003828812,0.0001293091,0.0006103928,0.0001229188,0.00008326558,0.0001973388],"genre_scores_gemma":[0.9987991,0.00004519878,0.0005506966,0.0001193342,0.00005778534,0.0001960063,0.00005486634,0.00002956493,0.0001473848],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7054406,"threshold_uncertainty_score":0.7622513,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01730378614014408,"score_gpt":0.2335730271823196,"score_spread":0.2162692410421755,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}