{"id":"W4319021623","doi":"10.1016/j.prro.2023.01.008","title":"Patterns of Progression in Patients With Newly Diagnosed Glioblastoma Treated With 5-mm Margins in a Phase 1/2 Trial of 5-Fraction Stereotactic Radiosurgery With Concurrent and Adjuvant Temozolomide","year":2023,"lang":"en","type":"article","venue":"Practical Radiation Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Medicine; Radiosurgery; Temozolomide; Tumor progression; Nuclear medicine; Progression-free survival; Radiation therapy; Glioblastoma; Confidence interval; Surgery; Chemotherapy; Internal medicine; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004312638,0.0003267571,0.0005917309,0.0004436721,0.0002811339,0.0005256028,0.0002530627,0.0003222791,0.0007278569],"category_scores_gemma":[0.000798545,0.0001832048,0.0004665655,0.0003738243,0.0002009375,0.0003838712,0.000224288,0.0004747527,0.00009891663],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00065832,"about_ca_system_score_gemma":0.0005251597,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002873191,"about_ca_topic_score_gemma":0.005245551,"domain_scores_codex":[0.9997754,0.0000753995,0.00001471552,0.00004746344,0.00003267401,0.00005452182],"domain_scores_gemma":[0.9996184,0.00007224542,0.0001344379,0.00002019915,0.00003552825,0.0001192254],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.08950724,0.002093598,0.84072,0.0001394147,0.0006326915,0.0005552766,0.0004583366,0.001316205,0.01640205,0.0001241994,0.0009979502,0.04705311],"study_design_scores_gemma":[0.00126661,0.009309737,0.9864645,0.000008272232,0.0001768536,0.0003913806,0.0001380446,0.0007695857,0.0007671485,0.00008567134,0.0006065572,0.00001563707],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992512,0.0002600811,0.000036522,0.00002259415,0.000007298008,0.00001937905,0.000133886,0.00000347328,0.0002655716],"genre_scores_gemma":[0.9991961,0.0001216119,0.00005264413,0.00003070398,0.000007970225,0.00002097707,0.0002984138,0.000002424098,0.0002692015],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002873191,"threshold_uncertainty_score":0.005712926,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02034030291252599,"score_gpt":0.352236745700516,"score_spread":0.33189644278799,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}