{"id":"W4319021623","doi":"10.1016/j.prro.2023.01.008","title":"Patterns of Progression in Patients With Newly Diagnosed Glioblastoma Treated With 5-mm Margins in a Phase 1/2 Trial of 5-Fraction Stereotactic Radiosurgery With Concurrent and Adjuvant Temozolomide","year":2023,"lang":"en","type":"article","venue":"Practical Radiation Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Medicine; Radiosurgery; Temozolomide; Tumor progression; Nuclear medicine; Progression-free survival; Radiation therapy; Glioblastoma; Confidence interval; Surgery; Chemotherapy; Internal medicine; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003066378,0.0001983718,0.0007567714,0.0005638628,0.00002361557,0.000009074196,0.00002656932,0.0001314223,0.00002889418],"category_scores_gemma":[0.0004569676,0.0001279446,0.0000335799,0.0006531774,0.00008258055,0.0002415695,0.00001698766,0.0002211175,0.000002365067],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000333736,"about_ca_system_score_gemma":0.0003104314,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001454453,"about_ca_topic_score_gemma":0.0003579301,"domain_scores_codex":[0.998157,0.0002942806,0.0005659058,0.0003403852,0.0003763444,0.0002661029],"domain_scores_gemma":[0.9974501,0.001494906,0.0006041884,0.0001705811,0.0001321123,0.0001480987],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.1113269,0.009420737,0.8070717,0.0000725233,0.0001367278,0.0006209865,0.0001980547,0.00002290344,0.0001014096,0.00002111307,0.0000298128,0.07097703],"study_design_scores_gemma":[0.2169157,0.02953834,0.7507955,0.0003469544,0.0002345621,0.00003184336,0.000159372,0.0006685115,0.001012233,0.000002328495,0.0001856997,0.0001089807],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967976,0.00003715942,0.0000372662,0.0009903107,0.00006223188,0.002001266,0.00002319004,0.00002478788,0.00002625178],"genre_scores_gemma":[0.9991279,0.0001488456,0.0001549833,0.00003526687,0.0000271612,0.0003447547,0.0001352027,0.00002374449,0.000002198711],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1055888,"threshold_uncertainty_score":0.5217428,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02034030291252599,"score_gpt":0.352236745700516,"score_spread":0.33189644278799,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}