{"id":"W4319080486","doi":"10.1038/s41380-023-01978-4","title":"The contribution of copy number variants to psychiatric symptoms and cognitive ability","year":2023,"lang":"en","type":"review","venue":"Molecular Psychiatry","topic":"Genomic variations and chromosomal abnormalities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":76,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Mental Health; U.S. Department of Health and Human Services","keywords":"Copy-number variation; Schizophrenia (object-oriented programming); Autism; Population; Autism spectrum disorder; Penetrance; Bipolar disorder; Cognition; Psychology; Intellectual disability; Psychiatry; Medicine; Phenotype; Genetics; Genome; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005173533,0.001052044,0.001714114,0.001500006,0.0001315018,0.0008754319,0.001010834,0.001057529,0.001956045],"category_scores_gemma":[0.001098892,0.0002035601,0.0005609094,0.001707628,0.00045422,0.0004697604,0.0004604439,0.00109641,0.0005191601],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004155508,"about_ca_system_score_gemma":0.0007159929,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002575918,"about_ca_topic_score_gemma":0.002582121,"domain_scores_codex":[0.9998242,0.00002952772,0.00002468642,0.00005566679,0.00005198552,0.000014],"domain_scores_gemma":[0.9996118,0.0002555398,0.00005010731,0.0000111618,0.0000525007,0.00001894965],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002323647,0.00003505728,0.002492762,0.007228531,0.0005887179,0.0008787315,0.00003316081,0.0006962385,0.001619031,0.001883854,0.01441012,0.9699014],"study_design_scores_gemma":[0.0001798937,0.0002224874,0.03844696,0.01057315,0.003927873,0.01673567,0.000194543,0.001067396,0.001867961,0.01228008,0.914351,0.0001529949],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002983391,0.9987109,0.0001675158,0.0002188336,0.00008166622,0.000001737255,0.00005474044,0.000005943176,0.0004603292],"genre_scores_gemma":[0.002563173,0.9962651,0.000276195,0.0001559617,0.0002608533,0.000004489308,0.00009541758,0.000001849205,0.0003769468],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002575918,"threshold_uncertainty_score":0.006543636,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008851974841897297,"score_gpt":0.2934226212282868,"score_spread":0.2845706463863895,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}