{"id":"W4319083386","doi":"10.1016/j.jaci.2022.12.064","title":"Impact Of Exacerbation History On Dupilumab Efficacy In Children With Asthma In The VOYAGE Study","year":2023,"lang":"en","type":"article","venue":"Journal of Allergy and Clinical Immunology","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine","funders":"","keywords":"Dupilumab; Exacerbation; Placebo; Medicine; Asthma; Internal medicine; Exhaled nitric oxide; Gastroenterology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001221032,0.0003282558,0.001111877,0.0002319428,0.0005519168,0.001208952,0.0004989785,0.0007501646,0.000914246],"category_scores_gemma":[0.001930213,0.0002418309,0.001703871,0.000442805,0.000400749,0.0006945567,0.0005919703,0.001309835,0.0001057207],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007123961,"about_ca_system_score_gemma":0.0006119562,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003564641,"about_ca_topic_score_gemma":0.009216599,"domain_scores_codex":[0.9992118,0.0002601916,0.00006488614,0.0001505519,0.0001196723,0.0001928082],"domain_scores_gemma":[0.998399,0.0004189309,0.0005764136,0.0001115548,0.00006825312,0.0004259199],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.02490869,0.0003807046,0.9577165,0.0002016956,0.002678855,0.0002235396,0.0001816567,0.0001715105,0.00128202,0.0001084856,0.0006770406,0.01146931],"study_design_scores_gemma":[0.001194531,0.002537512,0.9934596,0.00005168879,0.001260325,0.0002659132,0.0002262556,0.0001555256,0.000208648,0.00003557449,0.0005899914,0.00001446484],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997888,0.001411983,0.0000153334,0.00009374878,0.00002579201,0.000007443245,0.0002509874,0.000001920129,0.00030475],"genre_scores_gemma":[0.9992219,0.0002568374,0.00003172764,0.00006228472,0.0000247341,0.000007904309,0.0002619945,0.000001985839,0.0001305665],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003564641,"threshold_uncertainty_score":0.007087827,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02862012873526345,"score_gpt":0.346373279207607,"score_spread":0.3177531504723435,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}