{"id":"W4319297108","doi":"10.3390/curroncol30020152","title":"Application of CRISPR/Cas9 Technology in Cancer Treatment: A Future Direction","year":2023,"lang":"en","type":"review","venue":"Current Oncology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":76,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"CRISPR; Genome editing; Cas9; Computational biology; Gene; Genetic enhancement; Medicine; Biology; Bioinformatics; Genetics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006539499,0.0005806695,0.0009796917,0.001524661,0.000280075,0.0008849537,0.0007440166,0.00111933,0.004332329],"category_scores_gemma":[0.000494267,0.0002134033,0.0007378859,0.001427088,0.00055744,0.001512129,0.0005360129,0.002290495,0.001531591],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006705227,"about_ca_system_score_gemma":0.001225764,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001226616,"about_ca_topic_score_gemma":0.00239443,"domain_scores_codex":[0.9998122,0.00003722854,0.00001940256,0.00003545775,0.00007085133,0.0000249231],"domain_scores_gemma":[0.9996884,0.0001594683,0.00002825088,0.00001010607,0.00008220278,0.00003153305],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006172952,0.00007721482,0.0001670212,0.01346087,0.00006289439,0.0002459791,0.0000563442,0.0004403352,0.003971132,0.006210258,0.04494147,0.9303048],"study_design_scores_gemma":[0.0000149037,0.00009109708,0.000413111,0.001709922,0.00007243096,0.001026419,0.00005233555,0.0001524699,0.0008631801,0.00311341,0.9924718,0.00001887105],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000173007,0.9965705,0.0004128574,0.001183396,0.0003488448,0.000005856766,0.00002215675,0.00002047965,0.00126294],"genre_scores_gemma":[0.0008926369,0.9971952,0.0004883009,0.0005124133,0.0001627551,0.000006137646,0.00003387822,0.000002552281,0.0007060515],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004332329,"threshold_uncertainty_score":0.01449311,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06835177538779742,"score_gpt":0.4840187306555901,"score_spread":0.4156669552677927,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}