{"id":"W4319312920","doi":"10.1016/j.cell.2022.12.041","title":"Bacteriophages inhibit and evade cGAS-like immune function in bacteria","year":2023,"lang":"en","type":"article","venue":"Cell","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":133,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; Tsinghua University; National Natural Science Foundation of China; Searle Scholars Program; Chinese Academy of Sciences; European Molecular Biology Organization; University of Ottawa; Institute of Biophysics, Chinese Academy of Sciences; Broad Institute; National Science Foundation; Vallee Foundation; Damon Runyon Cancer Research Foundation; National Institutes of Health","keywords":"Biology; Bacteria; Immune system; Function (biology); Bacteriophage; Microbiology; Virology; Cell biology; Genetics; Escherichia coli; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001152533,0.0003419632,0.000174449,0.0001436838,0.00009425863,0.0002235992,0.0001093119,0.0002362872,0.0006855841],"category_scores_gemma":[0.00008739168,0.00008266686,0.0001431191,0.00006480166,0.0002078399,0.0001197086,0.0001905813,0.0003462378,0.0002606416],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001958481,"about_ca_system_score_gemma":0.0001254703,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001919806,"about_ca_topic_score_gemma":0.0002977943,"domain_scores_codex":[0.9998715,0.00002789606,0.00000723358,0.00001645285,0.00004307354,0.00003382013],"domain_scores_gemma":[0.9999375,0.00001360864,0.00001592459,0.000008055803,0.000007550309,0.00001731445],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002643413,0.000008205783,0.00009569871,0.00001309642,9.638574e-7,0.00001365976,0.000003951668,0.00001603478,0.9991774,0.00007454814,0.00001291776,0.0005571079],"study_design_scores_gemma":[0.00001192585,0.0002078832,0.004071294,0.000005380018,0.000004729123,0.0001841593,0.00001746477,0.0005044491,0.9931158,0.00007730978,0.001796921,0.000002608008],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9916658,0.002792925,0.002908195,0.00008839583,0.00003140279,0.00001774538,0.00006592047,0.00009147324,0.002338159],"genre_scores_gemma":[0.9957622,0.000611157,0.001455015,0.0000673278,0.00001114666,0.00001686172,0.00008453679,0.00001113474,0.001980523],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006855841,"threshold_uncertainty_score":0.002293468,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009608664159085688,"score_gpt":0.2180055707432726,"score_spread":0.2083969065841869,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}