{"id":"W4319312920","doi":"10.1016/j.cell.2022.12.041","title":"Bacteriophages inhibit and evade cGAS-like immune function in bacteria","year":2023,"lang":"en","type":"article","venue":"Cell","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":133,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; Tsinghua University; National Natural Science Foundation of China; Searle Scholars Program; Chinese Academy of Sciences; European Molecular Biology Organization; University of Ottawa; Institute of Biophysics, Chinese Academy of Sciences; Broad Institute; National Science Foundation; Vallee Foundation; Damon Runyon Cancer Research Foundation; National Institutes of Health","keywords":"Biology; Bacteria; Immune system; Function (biology); Bacteriophage; Microbiology; Virology; Cell biology; Genetics; Escherichia coli; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0002000025,0.0001300525,0.0001876982,0.0001961306,0.00007463816,0.00002025666,0.00008414676,0.0001718122,0.001315808],"category_scores_gemma":[0.00002175813,0.0001198041,0.00004232006,0.0001632623,0.00008963107,0.00008900234,0.0001061998,0.0001989703,0.002885631],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002039618,"about_ca_system_score_gemma":0.0000213773,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004963045,"about_ca_topic_score_gemma":0.00001132686,"domain_scores_codex":[0.9991243,0.00014908,0.0002162266,0.0002078267,0.00001518256,0.0002873951],"domain_scores_gemma":[0.9996752,0.00007491335,0.0000463038,0.0001747987,0.00001656959,0.00001224906],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003990012,0.00003377279,0.0004912469,0.00002612236,0.00001538142,0.000007863419,0.0003633903,3.136814e-7,0.9943647,0.0000170128,0.002163709,0.002117458],"study_design_scores_gemma":[0.00122288,0.0002254969,0.2351979,0.00003442809,0.00001015847,0.0000232567,0.0004137518,0.000002701666,0.6342017,0.0000235172,0.1284982,0.0001460943],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994132,0.002748543,0.000004053219,0.0001249235,0.001173115,0.0001162246,0.000009430128,0.00009673856,0.0015949],"genre_scores_gemma":[0.959267,0.0003859973,0.0000060671,0.0001006149,0.00001579691,0.00001478106,0.0001005597,0.00001576647,0.04009338],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.360163,"threshold_uncertainty_score":0.9995971,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009608664159085688,"score_gpt":0.2180055707432726,"score_spread":0.2083969065841869,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}