{"id":"W4319334289","doi":"10.1021/acs.jafc.2c08830","title":"Hydrogen Peroxide Produced from Selective Phenolic Acids in Cell Culture Underlies Caco-2 Changes in Cell Proliferation Parameters","year":2023,"lang":"en","type":"article","venue":"Journal of Agricultural and Food Chemistry","topic":"Essential Oils and Antimicrobial Activity","field":"Agricultural and Biological Sciences","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Gallic acid; Caffeic acid; Hydrogen peroxide; Chlorogenic acid; Chemistry; Autoxidation; Biochemistry; Caco-2; Cell growth; Cell culture; Ferulic acid; Apoptosis; Phenolic acid; Catalase; In vitro; Antioxidant; Food science; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001142585,0.0001875637,0.0002915071,0.00001649911,0.00008640624,0.00007858844,0.0001463467,0.0001993103,0.0000124692],"category_scores_gemma":[0.00002058094,0.00006969387,0.00008510341,0.0005021351,0.0000336714,0.000214181,0.00005077147,0.000412342,0.000002047293],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004841112,"about_ca_system_score_gemma":0.00001186267,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001258486,"about_ca_topic_score_gemma":0.0008268123,"domain_scores_codex":[0.9990019,0.00004444692,0.0002758056,0.0002443717,0.0001755636,0.0002579281],"domain_scores_gemma":[0.999517,0.00005532478,0.0002314276,0.0000262271,0.00008359582,0.00008637479],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003195195,0.000132168,0.004726999,0.00003546015,0.0000138883,0.000006572577,0.0008276431,0.00004989987,0.9933122,2.886383e-7,0.0002053941,0.000657576],"study_design_scores_gemma":[0.0003170702,0.0002207523,0.1060095,0.00006417659,0.00001559185,0.00001654709,0.002013753,0.000005610259,0.8910179,0.00009128846,0.0000579193,0.0001699131],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978939,0.0002716934,6.996088e-8,0.001496717,0.00004517057,0.0001161609,0.00003364322,0.00001801743,0.0001246044],"genre_scores_gemma":[0.9989253,0.0004177537,0.00002507863,0.00004661142,0.0003141061,0.000005707261,0.00005917173,0.00000134233,0.0002049154],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1022943,"threshold_uncertainty_score":0.2842034,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01239670931283159,"score_gpt":0.1924816044804044,"score_spread":0.1800848951675728,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}