{"id":"W4319334289","doi":"10.1021/acs.jafc.2c08830","title":"Hydrogen Peroxide Produced from Selective Phenolic Acids in Cell Culture Underlies Caco-2 Changes in Cell Proliferation Parameters","year":2023,"lang":"en","type":"article","venue":"Journal of Agricultural and Food Chemistry","topic":"Essential Oils and Antimicrobial Activity","field":"Agricultural and Biological Sciences","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Gallic acid; Caffeic acid; Hydrogen peroxide; Chlorogenic acid; Chemistry; Autoxidation; Biochemistry; Caco-2; Cell growth; Cell culture; Ferulic acid; Apoptosis; Phenolic acid; Catalase; In vitro; Antioxidant; Food science; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000376597,0.0004496183,0.0003592371,0.0002404621,0.0002198144,0.0003610966,0.0001652508,0.0003508884,0.001010135],"category_scores_gemma":[0.0002504276,0.0002541954,0.0002787391,0.0003455213,0.000309778,0.0002874934,0.0002183513,0.0007507599,0.0002848295],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002073977,"about_ca_system_score_gemma":0.0002048666,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009058547,"about_ca_topic_score_gemma":0.001879013,"domain_scores_codex":[0.9996839,0.00007984133,0.00003559482,0.00005604905,0.00008733768,0.00005724108],"domain_scores_gemma":[0.9997656,0.00006702666,0.00004925847,0.00003898297,0.00005031409,0.00002890638],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001318969,0.00002400422,0.0003431649,0.00003243784,0.000005279212,0.00002863067,0.0000379724,0.0000282178,0.9989352,0.00001333086,0.00001523693,0.0004046011],"study_design_scores_gemma":[0.000006323689,0.0003946097,0.006770313,0.000004652908,0.00002173475,0.00009204296,0.00006353034,0.0004000205,0.9915339,0.00002099861,0.0006866088,0.000005288792],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9895503,0.002401663,0.005318557,0.0001228094,0.00006288152,0.0000575462,0.0004715041,0.00006448171,0.001950296],"genre_scores_gemma":[0.9871089,0.002077347,0.006281684,0.0001007845,0.00002313423,0.0001344127,0.0009069751,0.00002193411,0.003344702],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001010135,"threshold_uncertainty_score":0.003379285,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01239670931283159,"score_gpt":0.1924816044804044,"score_spread":0.1800848951675728,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}