{"id":"W4319346644","doi":"10.1186/s13054-023-04310-2","title":"Rationale for sequential extracorporeal therapy (SET) in sepsis","year":2023,"lang":"en","type":"review","venue":"Critical Care","topic":"Mechanical Circulatory Support Devices","field":"Engineering","cited_by":77,"is_retracted":false,"has_abstract":true,"ca_institutions":"Tornado Spectral Systems (Canada)","funders":"","keywords":"Medicine; Sepsis; Extracorporeal; Extracorporeal membrane oxygenation; Intensive care medicine; Septic shock; Extracorporeal circulation; ARDS; Multiple organ dysfunction syndrome; Immunology; Hemofiltration; Organ dysfunction; Pathogen; Hemodialysis; Internal medicine; Lung","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001683096,0.0003406283,0.0009863497,0.0001694354,0.00004096666,0.000060763,0.0002618282,0.0004497951,0.0002822617],"category_scores_gemma":[0.0002300146,0.000322337,0.0004980728,0.0002679372,0.00004003946,0.00008073727,0.00002925761,0.0003634087,0.0001676658],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001914611,"about_ca_system_score_gemma":0.0001324421,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003013597,"about_ca_topic_score_gemma":0.00002968377,"domain_scores_codex":[0.9982931,0.00006333186,0.0006287941,0.0003843996,0.0002336931,0.0003966727],"domain_scores_gemma":[0.9986256,0.0008202099,0.00002704082,0.0002909496,0.00008940364,0.0001467665],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00000539447,0.00002523859,0.000008583409,0.142354,0.0001548165,0.0001786923,0.0002353507,0.00006678331,0.000002436895,0.01774928,0.00254576,0.8366736],"study_design_scores_gemma":[0.0001742633,0.00002686516,0.000002687833,0.002583384,0.0001697921,0.000008054736,0.0001026228,0.0003699124,0.00000563716,0.001476756,0.9946434,0.000436644],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00001013097,0.9959286,0.0006346078,0.00001449935,0.000774328,0.001175189,0.0006190933,0.0003308367,0.0005127441],"genre_scores_gemma":[0.0008717913,0.9942122,0.0003907415,0.00005367363,0.000709835,0.001740744,0.001707938,0.0002478758,0.00006523343],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9920976,"threshold_uncertainty_score":0.9999229,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2138981505808791,"score_gpt":0.4071690657280088,"score_spread":0.1932709151471297,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}